Evaluation of Tissue and Circulating microRNA Profiles in Patients With Hepatocellular Carcinoma Subjected to Thermal Ablation
Recruiting
Observational Study
Hepatocarcinoma
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 64
- Sex
- Any
- Study type
- Observational
- Participants needed
- 150 (estimated)
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna · Other
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About This Trial
The main objectives of this research project concern the identification of microRNAs circulating and of serum metabolites predictive of treatment response in patients with early stage hepatocellular carcinoma undergoing locoregional treatment with thermoablation.
In addition, the molecular mechanisms involved in reprogramming will be identified metabolic via bioinformatics analysis and pretreatme…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age ≥ 18
* Diagnosis of hepatocarcinoma confirmed by radiology (LIRADS criteria/triphasic diagnostics) or by biopsy.
* Indication for thermoablation treatment (for radiofrequency) based on the judgment of the hepatologist/surgeon.
* Informed consent signed by the patient.
Exc…
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