No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
50 – 80
Sex
Any
Study type
Interventional
Purpose
Supportive Care
Participants needed
60 (estimated)
Sponsor
Yale University · Other
Who this trial is looking for
This trial is looking for people with early Alzheimer's Disease, mild dementia, or mild cognitive impairment who also experience chronic pain. Participants will take part in group drumming sessions and will have their heart activity, brain activity, and pain responses measured before and after the sessions.
Are You a Good Fit for This Trial?
You may be able to join if
I have a diagnosis of early Alzheimer's Disease, mild dementia, or mild cognitive impairment.
I experience chronic pain that lasts more than 3 months.
I can give informed consent.
I am willing to wear health monitoring devices.
I am willing to answer survey questions related to the study.
I am willing to be recorded on audio and video.
I am willing to undergo cognitive testing and blood draws.
You may not be able to join if
I have a Clinical Dementia Rating lower than 0.5 or higher than 2.
I cannot provide informed consent.
I have thoughts of hurting myself or others.
I am currently participating in another clinical trial for Alzheimer's Disease or dementia.
I started a new prescription medication in the last 4 weeks.
I take medications that affect the central nervous system.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
This study aims to provide mechanistic insights into how group drumming as a music-based intervention (MBI) affects pain responses and nociceptive function in individuals with Alzheimer's Disease (AD), mild dementia or mild cognitive impairment (MCI). Heart rate (HR), heart rate variability (HRV), and brain activity will be measured during communal drumming with their dyadic partners and others. B…
This study aims to provide mechanistic insights into how group drumming as a music-based intervention (MBI) affects pain responses and nociceptive function in individuals with Alzheimer's Disease (AD), mild dementia or mild cognitive impairment (MCI). Heart rate (HR), heart rate variability (HRV), and brain activity will be measured during communal drumming with their dyadic partners and others. Brain activity, blood pressure, cognitive abilities, blood hormone levels, and static and dynamic pain will also be measured during sessions pre and post the 8-week community drum circle. Investigators will leverage various measurement techniques including, but not limited to, electroencephalography (EEG), quantitative sensory testing (QST), behavioral, surveys, and physiological monitoring to study the impact of group drumming on pain and brain activity in AD and inter-dyad synchrony.
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Eligibility Criteria
Inclusion Criteria:
* Clinical Dementia Rating 0.5 - 2
* Be a person with or caregiver to a person with a diagnosis of early Alzheimer's Disease, mild dementia, and/or mild cognitive impairment (MCI) and chronic pain defined as non-cancer pain lasting \>3 months that occurs most days and limits lif…
Inclusion Criteria:
* Clinical Dementia Rating 0.5 - 2
* Be a person with or caregiver to a person with a diagnosis of early Alzheimer's Disease, mild dementia, and/or mild cognitive impairment (MCI) and chronic pain defined as non-cancer pain lasting \>3 months that occurs most days and limits life or work activities OR Be a caregiver to a person with a diagnosis of early Alzheimer's Disease, mild dementia, and/or mild cognitive impairment (MCI) and chronic pain defined as non-cancer pain lasting \>3 months that occurs most days and limits life or work activities
* Able to provide informed consent
* Willing to wear an EEG headset and heart rate monitoring devices
* Willing to answer survey questions about topics related to the study
* Willing to be audio / video recorded
* Willing to undergo QST, blood draw, heart rate data collection and cognitive testing
Exclusion Criteria:
* Clinical Dementia Rating \<0.5 or \> 2
* Unable to provide informed consent
* Endorsing suicidal ideation (SI), self-injurious behavior, or homicidal ideation (HI) above the threshold defined in the "Risk Reduction and Safety Plan"
* Participating in another clinical trial studying AD and/or Dementia
* Starting a new prescription medication in the last 4 weeks
* Taking central nervous system acting medications that may interfere with study measurements as determined at PI discretion
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