The Effect of Different Intra-canal Medications on Postoperative Pain

Recruiting Early Phase 1 Interventional Study
Pulp Necrosis, Apical Periodontitis
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
18 – 40
Sex
Any
Trial phase
Early Phase 1
Study type
Interventional
Purpose
Treatment
Participants needed
111 (estimated)
Sponsor
Cairo University · Other
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About This Trial
The aim of this study is to assess the effect of ibuprofen, nitrofurantoin, and calcium hydroxide on postoperative pain after endodontic treatment of necrotic mandibular posterior teeth Research question/hypothesis: In patients with necrotic pulps in their mandibular posterior teeth, there would be no difference in the incidence and/or severity of postoperative pain after the use of ibuprofen, n…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Patients with necrotic pulps. 2. Adult, healthy patients, older than 18 years old 3. Males and females. 4. Patient with the ability to understand and use pain scales. 5. Patient who accepts enroll to the study. Exclusion Criteria: 1. Patients' allergies or any other contrai…
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