No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 55
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Basic Science
Participants needed
36 (estimated)
Sponsor
Eli Lilly and Company · Industry
Who this trial is looking for
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
The main purpose of this study is to compare 3 different forms of LY4065967 - a tablet and 2 types of capsule - to see how much and how quickly each gets into the bloodstream after it is swallowed, and to check for any side effects. For each participant, the study will last about 7 weeks and will include 3 stays in the Clinical Research Unit (CRU). Each stay will last 3 nights.
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
* Are overtly healthy as determined by medical evaluation including medical history, physical examination, and laboratory tests.
* Have clinical laboratory test results within normal reference range for the population or investigative site.
* Have an electrocardiogram (ECG) at s…
Inclusion Criteria:
* Are overtly healthy as determined by medical evaluation including medical history, physical examination, and laboratory tests.
* Have clinical laboratory test results within normal reference range for the population or investigative site.
* Have an electrocardiogram (ECG) at screening considered to be within acceptable limits by the investigator.
* Have a body mass index within the range 18.0 to 35.0 kilograms per square meter (kg/m²) (inclusive).
* Individuals assigned male at birth (AMAB) or assigned female at birth (AFAB) may participate in this trial.
* Have venous access sufficient to allow for blood sampling.
Exclusion Criteria:
* Have a history of or current clinically significant medical conditions, including cardiovascular disease, electrolyte abnormalities, respiratory, hepatic, renal, gastrointestinal, endocrine, hematologic, or neurologic disorders that, in the judgment of the investigator, could predispose to arrhythmia, pose a risk with study participation, significantly alter the absorption, metabolism, or elimination of the study drug, or interfere with the interpretation of study data.
* Have systolic blood pressure of 140 millimeters of mercury (mmHg) or greater and diastolic blood pressure of 90 mmHg or greater at screening.
* Have a history of clinically significant known allergies to LY4065967, related compounds, or any components of the formulation, or history of significant atopy.
* Have a history of alcohol, opioids, stimulants or hallucinogens use disorder within 2 years prior to screening or a current use disorder by Diagnostic and Statistical Manual of Mental Disorders (APA 2013).
Contacts
Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or
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