Dalpiciclib with Anti-HER2 Therapy for Breast Cancer

Dalpiciclib, Anti-HER2 Therapy, and Endocrine Therapy for Hormone-Receptor-Positive, HER2-Positive Metastatic Breast Cancer

Recruiting Phase 2 Interventional Study
Advanced/Metastatic Breast Cancer HER2-Positive Metastatic Breast Cancer
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 75
Sex
Female
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
57 (estimated)
Sponsor
Sun Yat-sen University · Other
Who this trial is looking for

This trial is looking for women with a specific type of advanced breast cancer who have had some treatment already. If eligible, participants will receive a combination of drugs to manage their condition.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am a female aged 18 to 75 years old.
  • I have been diagnosed with metastatic or locally advanced unresectable breast cancer.
  • My breast cancer is hormone receptor-positive and HER2-positive.
  • I have had 4-8 cycles of anti-tumor therapy without disease progression.
  • My overall health is good (ECOG 0-1 status).

You may not be able to join if

  • I have active brain metastases or extensive leptomeningeal metastases.
  • I have had a serious allergic reaction to the study drugs.
  • I am currently receiving other anti-tumor therapies.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer a few quick questions to see if you may meet the eligibility requirements.

Check Your Eligibility
About This Trial

Efficacy and Safety of Dalpiciclib Combined with Anti-HER2 Targeted Therapy and Endocrine Therapy as First-line Maintenance Treatment for Patients with Recurrent or Metastatic Hormone-Receptor-Positive, HER2-positive Breast Cancer.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Females aged 18 to 75 years with pathologically confirmed metastatic or locally advanced unresectable breast cancer. 2. Hormone receptor (HR)-positive and HER2-positive. 3. Patients with no evidence of disease progression (including CR, PR, or SD)after 4-8 cycles of first-lin…
Contacts

Chen Doctor Chen, PhD / Doctorate

02087341812

chenmt@sysucc.org.cn

CONTACT