Dupilumab for Chronic Obstructive Pulmonary Disease (COPD)
The Study of Chronic Obstructive Pulmonary Disease (COPD) Participants Treated With Dupilumab (STRIDE) Registry
Recruiting
Observational Study
COPD (Chronic Obstructive Pulmonary Disease)
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
40 and older
Sex
Any
Study type
Observational
Participants needed
350 (estimated)
Sponsor
Sanofi · Industry
Who this trial is looking for
This trial is looking for people with Chronic Obstructive Pulmonary Disease (COPD) who are starting treatment with dupilumab. Participants will share their experiences and health information to help assess the treatment's effectiveness and safety.
Are You a Good Fit for This Trial?
You may be able to join if
I have been diagnosed with COPD.
I am 40 years old or older.
I am newly referred to start treatment with dupilumab.
I have had a standard spirometry test within 90 days before joining the study.
You may not be able to join if
I have a condition that prevents me from participating in the study.
I have a short life expectancy.
I am currently participating in another clinical trial.
I have a contraindication to dupilumab.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
The STRIDE Registry will evaluate the real-world effectiveness and safety of dupilumab in participants with COPD. The primary objective is to describe characteristics of participants newly initiated with dupilumab for COPD. Secondary objectives are to determine whether treatment with dupilumab reduces moderate and/or severe COPD exacerbations; to determine the impact of treatment on lung function …
The STRIDE Registry will evaluate the real-world effectiveness and safety of dupilumab in participants with COPD. The primary objective is to describe characteristics of participants newly initiated with dupilumab for COPD. Secondary objectives are to determine whether treatment with dupilumab reduces moderate and/or severe COPD exacerbations; to determine the impact of treatment on lung function in COPD participants; to determine whether treatment with dupilumab improves the quality of life in COPD participants; and to describe safety of dupilumab among COPD participants. The external control cohort will include participants with COPD from the National Patient-Centered Clinical Research Network (PCORnet) consortium who are not being treated with dupilumab. In addition, chest images will be collected and banked for future research projects and consented participants will perform home spirometry.
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
* COPD patients who are newly referred to start dupilumab treatment
* Age ≥ 40 years
* Standard of care spirometry performed concurrently with the baseline visit or within 90 days prior to the baseline visit
Exclusion Criteria:
* Patients who have contraindication to dupilumab…
Inclusion Criteria:
* COPD patients who are newly referred to start dupilumab treatment
* Age ≥ 40 years
* Standard of care spirometry performed concurrently with the baseline visit or within 90 days prior to the baseline visit
Exclusion Criteria:
* Patients who have contraindication to dupilumab according to the United States Prescribing Information (USPI)
* Any condition that, in the opinion of the Investigator, may interfere with the patient's ability to participate in the study, such as short life expectancy, or other comorbidities that can predictably prevent the patient from completing the schedule of assessments
* Patients currently participating in any interventional clinical trial The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial
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