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Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 65
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
80 (estimated)
Sponsor
Ankara Etlik City Hospital · Government
Who this trial is looking for
This trial is looking for adults aged 18 to 65 who need surgery for a lumbar disc herniation. Participants will receive either flow-controlled or volume-controlled ventilation during the procedure, and their breathing measurements will be taken after they are put under anesthesia.
Are You a Good Fit for This Trial?
You may be able to join if
I am between 18 and 65 years old
I am classified as ASA physical status I, II, or III
My body mass index is between 18 and 30 kg/m²
You may not be able to join if
I am younger than 18 or older than 65 years old
I have a known or previously diagnosed lung disease
I have severe pulmonary function issues
I have had major thoracic surgery that changed my lung function
I was using supplemental oxygen before the surgery
I am classified as ASA physical status IV or higher
I refuse or cannot provide informed consent
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
This prospective randomized trial aims to compare the effects of flow-controlled ventilation (FCV) and volume-controlled ventilation (VCV) on intraoperative airway pressures and oxygenation in patients undergoing lumbar disc herniation surgery under general anesthesia.
Adult patients aged 18-65 years, with ASA physical status I-III and a body mass index of 18-30 kg/m², will be allocated to receiv…
This prospective randomized trial aims to compare the effects of flow-controlled ventilation (FCV) and volume-controlled ventilation (VCV) on intraoperative airway pressures and oxygenation in patients undergoing lumbar disc herniation surgery under general anesthesia.
Adult patients aged 18-65 years, with ASA physical status I-III and a body mass index of 18-30 kg/m², will be allocated to receive either FCV or VCV during routine intraoperative mechanical ventilation. Ventilatory parameters, including peak airway pressure, plateau pressure, pulmonary compliance, EtCO₂, SpO₂, and arterial blood gas variables, will be recorded at predefined time points after intubation.
The primary endpoint is the PaO₂ value measured after 20 minutes in the prone position.
By comparing respiratory mechanics and oxygenation between the two ventilation modes, this study aims to contribute to the optimization of intraoperative ventilatory management in lumbar disc herniation surgery.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age between 18 and 65 years
* ASA physical status I-III
* Body Mass Index between 18 and 30 kg/m²
Exclusion Criteria:
* Age \< 18 years or \> 65 years
* Known or previously diagnosed pulmonary disease
* Patients with severe preoperative pulmonary function impairment (e.g., F…
Inclusion Criteria:
* Age between 18 and 65 years
* ASA physical status I-III
* Body Mass Index between 18 and 30 kg/m²
Exclusion Criteria:
* Age \< 18 years or \> 65 years
* Known or previously diagnosed pulmonary disease
* Patients with severe preoperative pulmonary function impairment (e.g., FEV₁ \< 50% predicted, severe restrictive or obstructive pathology)
* Patients with markedly altered lung anatomy or function due to prior major thoracic surgery
* Patients who were dependent on supplemental oxygen therapy in the preoperative period
* ASA physical status IV or higher
* Refusal or inability to provide informed consent
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