Higher Radiation Dose to the Tumor May Help Avoid Surgery in Rectal Cancer Patients

Recruiting N/A Interventional Study
Rectal Cancer Radiation Oncology
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
25 (estimated)
Sponsor
Claudia Schuurhuizen · Other
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About This Trial

The goal of this prospective study is to evaluate if a higher radiation dose to the tumor can increase the organ preservation rate in non-locally advanced rectal cancer.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age ≥18 years * Eastern cooperative oncology group (ECOG) performance status ≤2 * Histologically confirmed rectal adenocarcinoma * Non-locally advanced rectal cancer, defined as (magnetic resonance imaging (MRI)-based) T1-3, N0/N1 (≤3 positive mesorectal lymph nodes), MX/M0 * …
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