Natural History of Atrial Fibrillation-Induced Tricuspid Valve Remodeling in the Absence of Significant Tricuspid Regurgitation: A Three-Dimensional Echocardiographic Study
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
66 (estimated)
Sponsor
Centro Cardiologico Monzino · Other
Who this trial is looking for
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This is a prospective, observational, multicenter study aimed at characterizing tricuspid valve remodeling in patients with atrial fibrillation (AF) without significant tricuspid regurgitation (TR), in relation to AF burden progression.
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
* Consecutive patients with atrial fibrillation (paroxysmal or persistent) undergoing transthoracic echocardiography (TTE) prior to AF ablation with acquisition of a 3D TV dataset.
Eligible for enrollment in the control group will be:
1. all consecutive patients with structura…
Inclusion Criteria:
* Consecutive patients with atrial fibrillation (paroxysmal or persistent) undergoing transthoracic echocardiography (TTE) prior to AF ablation with acquisition of a 3D TV dataset.
Eligible for enrollment in the control group will be:
1. all consecutive patients with structurally normal hearts and no history of AF or;
2. moderate atrial functional tricuspid regurgitation and AF, in the absence of significant left-sided valvular disease or prior valvular surgery.
Exclusion Criteria:
* Moderate or greater TR assessed using a multiparametric approach;
* Arrhythmias other than AF;
* Prior AF ablations;
* Rapid ventricular response (average HR \>110 bpm) during baseline TTE;
* Inadequate image quality
Contacts
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