Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
40 – 70
Sex
Any
Study type
Interventional
Purpose
Prevention
Participants needed
82 (estimated)
Sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology · Industry
Who this trial is looking for
This trial is looking for adults aged 40-70 years with prediabetes or insulin resistance. Participants will eat meals mainly made of avocados and attend clinic visits while maintaining their usual activities.
Are You a Good Fit for This Trial?
You may be able to join if
I am 40-70 years old.
My fasting triglycerides are above 115 mg/dL.
I have insulin resistance with a HOMA-IR above 2.5.
I can provide informed consent.
I can eat almost all the meals provided by the study.
I can come to the clinic up to 6 times during the study.
I can avoid alcohol and vigorous exercise 24 hours before visits.
You may not be able to join if
I have allergies or intolerances to avocados or related foods.
My fasting blood sugar is 125 mg/dL or higher.
I have had any major health issues or surgeries in the last year.
I have had cancer (except non-melanoma skin cancer) in the past 5 years.
I am on a special diet like vegan or keto.
I am not weight stable within 10 lbs over the last 2 months.
I am pregnant or planning to become pregnant during the study.
I use excessive drugs or alcohol.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
In this study, Investigators are interested in looking at the influence of eating avocados regularly, which are rich in healthy fats, fibers, and unique carbohydrates, on triglyceride and glucose metabolism in people with prediabetes and insulin resistance.
Trial Locations
Loading…
Loading trial locations…
Facility
City
State
Country
Status
Eligibility Criteria
Inclusion Criteria:
* Men or women, 40-70 years of age.
* Fasting triglycerides (TG) \>115 mg/dL.
* Insulin resistance as measured by Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) \>2.5.
* Able to provide informed consent.
* Able to comply with and perform the procedures requested b…
Inclusion Criteria:
* Men or women, 40-70 years of age.
* Fasting triglycerides (TG) \>115 mg/dL.
* Insulin resistance as measured by Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) \>2.5.
* Able to provide informed consent.
* Able to comply with and perform the procedures requested by the protocol, specifically eat all the meals and snacks provided by the study which will be almost all your food (\~ 80% of calories per day).
* Able to come to the clinic up to 6 times during the study.
* Able to maintain usual physical activity pattern.
* Able to avoid/abstain from alcohol and vigorous physical activity for 24 hours prior to and during study visit.
Exclusion Criteria:
* Men and women with known or suspected intolerance, allergies or hypersensitivity to study foods or interventions.
* Fasting blood sugar ≥125 mg/dL. Men and women with blood pressure \>160 mmHg (systolic) / 100 mmHg (diastolic) at the screening visit.
* Men and women with history of diabetes cardiovascular events, respiratory, renal, gastrointestinal, hepatic or eye disease or surgery- within a year.
* Men and women who have or had cancer other than non-melanoma skin cancer in the past 5 years.
* Men and women taking over the counter or prescription medications or dietary supplements that may interfere with study procedures or endpoints.
* Men and women who are on a specialized diet (vegan, vegetarian, keto, etc.). - - Men and women who consume nuts or peanuts daily or most days of the week.
* Men and women who are not weight stable (+/-10lbs in previous 2 months). Men and women who have excessive use of drugs or alcohol (ie., addictions) within the past 2 years.
* Men and women with documented physical or mental disease/condition, which might limit participation in or completion of the study or, that, in the opinion of the investigator, could interfere with the interpretation of the study results.
* Women who are known to be pregnant or who are intending to become pregnant over the course of the study.
* Women who are lactating.
* Major trauma or a surgical event within 2 months (or longer depending on trauma or event) and after consultation with PI. Has used antibiotics within the previous 2 months.
* History of an eating disorder (e.g., anorexia nervosa, bulimia nervosa, or binge eating) diagnosed by a health professional.
* Excessive coffee and tea consumers (\> 4 cups/d).
* Donated blood within the last 3 months.
* Women who are taking an unstable dose and brand of hormonal contraceptives and/or a stable dose and brand for less than 6 months.
* Unusual working hours (working overnight).
Picking one helps us show the most relevant trials first.
Your results are loading in the background — you can
change this any time from the results page.
Set your location to continue
Find My Trials uses your location to surface clinical trials near you.
Add your city or zip code to your profile and try again.