Imaging for Knee Osteoarthritis Pain

FDG PET/MRI Imaging of Patellofemoral Joint Osteoarthritis

Recruiting Observational Study
Patellofemoral Osteoarthritis Knee Osteoarthritis Knee Pain Inflamation
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
50 (estimated)
Sponsor
University of California, San Francisco · Other
Who this trial is looking for

This trial is looking for adults with knee osteoarthritis who can perform physical tasks and do not have recent knee injuries. Participants will undergo imaging tests to help better understand their knee pain.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am an adult and can give informed consent.
  • I can perform 25 single-leg squats.
  • I have not had recent knee injuries or surgeries.
  • I am not taking investigational drugs.
  • I have no contraindications to MRI or PET tracing.
  • I am not taking steroid injections.
  • I am not pregnant.
  • I have minimal pain during single-leg squats.

You may not be able to join if

  • I cannot consent for myself.
  • I cannot perform 25 single-leg squats with the study leg.
  • I have had recent knee injuries or surgeries.
  • I am taking investigational drugs.
  • I have new contraindications to MRI or PET tracing.
  • I am taking steroid injections.
  • I am pregnant.
  • I have diabetes.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

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About This Trial
This project aims to develop an \[18F\] fluorodeoxyglucose (FDG) positron emission tomography (PET) / magnetic resonance imaging (MRI) method to locate the painful inflammation in PFJ OA associated with joint loading. \[18F\] FDG PET/MRI is an emerging pain imaging approach with enhanced sensitivity to painful hypermetabolic inflammation through evaluation of intracellular glucose utilization rate…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Adult with the capacity to give informed consent * Ability to perform 25 single-leg squats * No traumatic knee injuries/surgeries since last visit for the parent study (IRB #21-34763) * No investigational drugs since last visit for the parent study (IRB #21-34763) * No contrai…
Contacts

Eric Hammond

415-502-6470

eric.hammond@ucsf.edu

CONTACT