Branched Chain Amino Acids for Sarcopenia in Patients Undergoing Total Knee Arthroplasty
Recruiting
Phase 4
Interventional Study
Sarcopenia
Total Knee Arthroplasty
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 40 – 100
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 140 (estimated)
- Sponsor
- Seoul National University Hospital · Other
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About This Trial
This multicenter, prospective, randomized controlled trial evaluates whether postoperative administration of branched chain amino acids affects skeletal muscle mass index and sarcopenia related functional outcomes in patients undergoing total knee arthroplasty.
Participants are randomly assigned to receive Livact granules 4.15 g three times daily for 3 months after surgery or to receive standard …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1\. Patients aged 40 to 100 years who are scheduled to undergo total knee arthroplasty.
Exclusion Criteria:
1. Participants who used antiretroviral agents within 4 weeks before the first administration of Livact.
2. Participants who used medications associated with fatty liver…
Contacts