A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With Obesity
Recruiting
Phase 2Interventional Study
Obesity
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
230 (estimated)
Sponsor
Novo Nordisk A/S · Industry
Who this trial is looking for
This trial is looking for adults with obesity who want to lose weight. Participants will take a treatment called NNC0662-0419 to see if it helps them safely lose weight.
Are You a Good Fit for This Trial?
Rules you outType 1 diabetesType 2 diabetes
You may be able to join if
I am 18 years or older
I have a body mass index (BMI) of 30 or more
I want to lose at least 25% of my body weight
You may not be able to join if
I am allergic to the treatment or similar products
I have taken any weight loss medications in the last 90 days
My glycated hemoglobin (HbA1c) is 6.5% or higher
I have a history of type 1 or type 2 diabetes
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
The purpose of the study is to find out if NNC0662-0419 is safe and effective for treating participants living with obesity.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Male or female (sex assigned at birth, inclusive of all gender identities).
* Age 18 years or above at the time of signing the informed consent.
* Body mass index (BMI) greater than or equal to (≥) 30.0 kilogram per square meter (kg/m\^2) at screening.
* Participant must have …
Inclusion Criteria:
* Male or female (sex assigned at birth, inclusive of all gender identities).
* Age 18 years or above at the time of signing the informed consent.
* Body mass index (BMI) greater than or equal to (≥) 30.0 kilogram per square meter (kg/m\^2) at screening.
* Participant must have a desire and be committed to lose at least 25 percentage (%) of their body weight from randomisation.
Exclusion Criteria:
* Known or suspected hypersensitivity to study intervention(s) or related products.
* Treatment with any medication prescribed for the indication of obesity or weight management (e.g. glucagon-like-peptide-1 (GLP-1) receptor agonists (RA), dual GLP-1/gastric inhibitory peptide (GIP) RAs (or any other GLP-1 based treatment) or amylin analogues)) within 90 days before screening.
* Glycated haemoglobin (HbA1c) ≥ 6.5% (48 Millimoles per mole \[mmol/mol\]) as measured by the central laboratory at screening.
* History of type 1 or type 2 diabetes mellitus.
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