Genetic, Microbiological and Behavioral Factors in Obesity
Recruiting
Observational Study
Obesity & OverweightObesityGenetics
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 60
Sex
Any
Study type
Observational
Participants needed
200 (estimated)
Sponsor
Jan Kochanowski University · Other
Who this trial is looking for
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This study will assess the impact of genetic markers, microbiological (microbiome) and behavioral factors on tolerance, adherence and effectiveness of dual GLP1/GIP RA in the treatment of obesity.
200 consecutive patients who meet all inclusion and none of the exclusion criteria will be enrolled.
Trial Locations
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Eligibility Criteria
Inclusion criteria
* Age 18-60 years
* Consent to participate in the study and providing informed written consent
* Overweight or obese with a BMI \>27
Exclusion criteria
* Contraindications to tirzepatide use:
* Type 1 or type 2 diabetes
* Pregnancy or breastfeeding
* Cancer
* Heart failure
* Ex…
Inclusion criteria
* Age 18-60 years
* Consent to participate in the study and providing informed written consent
* Overweight or obese with a BMI \>27
Exclusion criteria
* Contraindications to tirzepatide use:
* Type 1 or type 2 diabetes
* Pregnancy or breastfeeding
* Cancer
* Heart failure
* Expected lack of patient compliance
* Taking immunosuppressive medications, steroids, NSAIDs, antibiotics (within 2 weeks prior to sample collection),
* Autoimmune and inflammatory diseases, acute infectious diseases, AIDS, tuberculosis
* Mental illness
* Alcohol dependence syndrome
* Liver cirrhosis
* Post-myocardial infarction or stroke
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