Brain and Sensory Stimulation for Primary Progressive Aphasia
Stimulating the Aging Brain Using Brain and Sensory Stimulation
Recruiting
N/A
Interventional Study
Primary Progressive Aphasia
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 45 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 20 (estimated)
- Sponsor
- Medical College of Wisconsin · Other
Who this trial is looking for
This trial is looking for people with primary progressive aphasia (PPA) to see how brain and sensory stimulation can help with language skills. Participants will have tests like EEG and MRI, and receive brain stimulation over three sessions while completing language tasks.
Are You a Good Fit for This Trial?
You may be able to join if
- I have been diagnosed with primary progressive aphasia or mild cognitive impairment.
- I have not had problems with daily living activities.
- I completed a cognitive exam or neuropsychological test in the last 6 months.
You may not be able to join if
- I have evidence of dementia.
- I have a history of cancer, significant stroke, or serious brain injury.
- I am under 45 years old.
- I have severe psychiatric illness.
- I have a cardiac pacemaker or other head/eye implants.
- I cannot undergo MRI or brain stimulation.
- I am pregnant.
- I have a history of unmanaged seizures or dyslexia.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
The goal of this project is to investigate whether transcranial electrical stimulation and sensory stimulation affect language outcomes in individuals with primary progressive aphasia (PPA). The main questions it aims to answer are:
Does transcranial alternating current stimulation (tACS) affect verbal short-term memory (STM) in individuals with PPA? Does a single session of multisensory stimulat…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Clinical exam supports diagnosis of PPA and/or MCI with no report of difficulty functioning in basic or instrumental activities of daily living.
* Completed clinical cognitive exam within 6 months of study baseline visit OR neuropsychological research battery within 6 months o…
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