Tamsulosin Dose Escalation or Silodosin Switch Before Trial Without Catheter in BPH-Related Acute Urinary Retention
Recruiting
Phase 4
Interventional Study
Acute Urinary Retention
Benign Prostatic Hyperplasia
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 50 and older
- Sex
- Male
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 378 (estimated)
- Sponsor
- Beni-Suef University · Other
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About This Trial
This randomized controlled trial will compare three medication strategies before trial without catheter in men with acute urinary retention due to benign prostatic hyperplasia who were already taking tamsulosin 0.4 mg once daily before the retention episode. After urethral catheterization, eligible participants will be randomly assigned to one of three groups for 7 days: continuation of tamsulosin…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Male patients aged 50 years or older.
* Acute urinary retention requiring urethral catheterization.
* Presumed acute urinary retention secondary to benign prostatic enlargement or benign prostatic obstruction.
* Already receiving tamsulosin 0.4 mg once daily for at least 4 wee…
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