Toxin Exposure and Immune Dysregulation in Non-Hodgkin Lymphoma
Recruiting
Observational Study
Non-Hodgkin Lymphoma
Lymphoma Non-Hodgkin
B-cell Lymphoma
Immune Dysregulation
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 4 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 300 (estimated)
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine · Other
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About This Trial
The goal of this observational cohort study is to learn how toxin and occupational exposures, germline genetic variation, and immune dysregulation relate to B-cell non-Hodgkin lymphoma among active-duty service members and other Military Health System beneficiaries. The main questions are whether specific exposures and germline variants are associated with B-cell NHL subtype, immune dysfunction, a…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age 4 years old and older with a clinical diagnosis of B-cell NHL.
* Must be willing to undergo phlebotomy and/or skin punch biopsy.
* Must be willing to undergo whole genome sequencing, which includes return of primary and secondary findings.
Exclusion Criteria:
* Has any c…
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