Impact of Steatotic Liver Disease Associated With Metabolic Dysfunction (MASLD) on Frailty, Cognition, and Quality of Life. A Gender-sensitive Approach Towards a Comprehensive and Equitable Perspective.
Recruiting
Observational Study
Steatosis of Liver
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
20 – 80
Sex
Any
Study type
Observational
Participants needed
140 (estimated)
Sponsor
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau · Other
Who this trial is looking for
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The goal of this observational study is to determine the differences in the prevalence, characteristics and evolution of frailty between men and women diagnosed with MASLD, and to establish its relationship with clinical, functional, hormonal and social parameters.
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Eligibility Criteria
Inclusion Criteria:
* Patients will be included who are able to provide informed consent and actively participate in periodic assessments.
Exclusion Criteria:
* Risky alcohol consumption:
\> 30 g/day in men and \> 20 g/day in women. AUDIT score: \> 7 points in men, \> 5 in women.
* Other liver …
Inclusion Criteria:
* Patients will be included who are able to provide informed consent and actively participate in periodic assessments.
Exclusion Criteria:
* Risky alcohol consumption:
\> 30 g/day in men and \> 20 g/day in women. AUDIT score: \> 7 points in men, \> 5 in women.
* Other liver diseases (viral hepatitis, autoimmune hepatitis, etc.).
* Advanced neurodegenerative diseases or severe psychiatric disorders.
* Severe comorbidities or treatments that, in the researchers' judgment, may affect frailty and quality of life more than metabolic syndrome and liver disease.
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