VYD2311 Vaccine for COVID-19

Safety and Serum Virus Neutralizing Antibody Responses of VYD2311, a COVID-19 Vaccine, and Coadministered VYD2311 With a COVID-19 Vaccine

Recruiting Phase 3 Interventional Study
COVID-19
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 49
Sex
Any
Trial phase
Phase 3
Study type
Interventional
Purpose
Prevention
Participants needed
210 (estimated)
Sponsor
Invivyd, Inc. · Industry
Who this trial is looking for

This trial is looking for healthy adults aged 18 to 49 to see how safe the VYD2311 vaccine is and how it works in the body. Participants will receive either the VYD2311 vaccine, a COVID-19 vaccine, or both and will be monitored for any side effects.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am a healthy adult aged 18 to 49 years
  • I weigh at least 40 kg
  • I have a BMI between 18.0 and 32.0
  • I am in good health according to medical checks

You may not be able to join if

  • I have had VYD2311 or pemivibart before
  • I have received a COVID-19 vaccine in the past 6 months
  • I have received a non-COVID-19 vaccine in the past 28 days
  • I have had convalescent plasma or SARS-CoV-2 mAb in the past 6 months
  • I have known or suspected SARS-CoV-2 infection in the past 6 months
  • I tested positive for SARS-CoV-2 on Day 0
  • I have been in close contact with someone with SARS-CoV-2 in the last 5 days
  • I am currently ill with symptoms of SARS-CoV-2 or have a fever in the last 14 days

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer a few quick questions to see if you may meet the eligibility requirements.

Check Your Eligibility
About This Trial
The main purposes of this research study are to measure the safety (whether it causes any side effects), tolerability (if it does cause any side effects, how well your body is able to handle them), and reactions, both local at the injection site and systemic, that may occur in the body after receiving VYD2311, or a COVID-19 vaccine, or a combination of VYD2311 and a COVID-19 vaccine in healthy par…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Is a healthy adult male or female aged 18 to 49 years, inclusive, weighing at least 40 kg at the time of Screening 2. Has a body mass index (BMI) 18.0 to 32.0 mg/kg2, inclusive. 3. Is in good health, with no clinically significant abnormalities as determined by the Investigat…
Contacts

Study Inquiry

+1 781-819-0080

clinicaltrials@invivyd.com

CONTACT