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Elecoglipron for Type 2 Diabetes Management

A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus on Background Insulin

Recruiting Phase 3 Interventional Study
Type 2 Diabetes Mellitus
More trials: Diabetes clinical trials· Diabetes trials in Florida
Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 3
Study type
Interventional
Purpose
Treatment
Participants needed
600 (estimated)
Sponsor
AstraZeneca · Industry
Who this trial is looking for

This trial is looking for adults with type 2 diabetes who are already taking insulin and other medications to lower blood sugar. Participants will compare a new treatment called elecoglipron with a placebo to see how effective and safe it is.

Are You a Good Fit for This Trial?
Must be taking Insulin
Rules you out Type 1 diabetesDiabetic retinopathyPancreatitisSevere heart failureMedullary thyroid cancer

You may be able to join if

  • I have been diagnosed with type 2 diabetes for at least 90 days.
  • I am currently taking background insulin and other diabetes medications.
  • My HbA1c value is between 7% and 10.5%.
  • My body mass index (BMI) is at least 23.
  • I have maintained a stable body weight for the last 90 days.

You may not be able to join if

  • I have type 1 diabetes or another form of diabetes.
  • I am receiving treatment for diabetic eye problems.
  • I have had more than one severe low blood sugar episode in the last 180 days.
  • I have significant issues with my upper GI tract.
  • I have a history of pancreatitis.
  • I have severe heart failure.
  • I have a history of medullary thyroid cancer in myself or family.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial

The purpose of this study is to evaluate the efficacy, safety, and tolerability of elecoglipron compared with placebo in adults with Type 2 Diabetes Mellitus (T2DM), treated with a background insulin and other background glucose-lowering medication(s)

Trial Locations

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Eligibility Criteria
Inclusion Criteria: * Diagnosed with T2DM for at least 90 days prior to screening * Stable treatment with background insulin and other background glucose-lowering medication(s) * HbA1c value of ≥ 7% to ≤ 10.5% * Body mass index (BMI) of ≥ 23 kg/m2 at screening * Stable body weight (self-reported or…
Contacts

AstraZeneca Clinical Study Information Center

1-877-240-9479

information.center@astrazeneca.com

CONTACT

NCT ID: NCT07664553 Source: ClinicalTrials.gov