Vitamin D2 vs Vitamin D2 Plus Calcitriol in Cholestatic Children With Vitamin D Deficiency
Recruiting
Phase 4
Interventional Study
Cholestatic Liver Disease
Chronic Liver Disease (CLD)
Vitamin D Deficiency
Children
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- Up to 18
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 54 (estimated)
- Sponsor
- Chulalongkorn University · Other
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About This Trial
The goal of this clinical trial is to learn whether adding calcitriol to vitamin D2 can improve vitamin D deficiency in children with cholestasis and chronic liver disease. Cholestasis is a condition in which bile flow is reduced, which can make it difficult for the body to absorb and process vitamin D. The study will also learn about the safety of using vitamin D2 together with calcitriol.
The m…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patients younger than 18 years of age.
* Patients diagnosed with cholestasis, defined as direct/conjugated bilirubin \>1 mg/dL for more than 1 month.
* Patients diagnosed with chronic liver disease.
* Patients with vitamin D deficiency, defined as serum 25-hydroxyvitamin D (25…
Contacts