No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
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At a Glance
Age
18 – 65
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
24 (estimated)
Sponsor
Medipol University · Other
Who this trial is looking for
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This study evaluates the antibacterial effectiveness of two different intracanal medicaments, Bio-C Temp and UltraCal XS , in mandibular molar teeth with chronic apical periodontitis. Intracanal bacterial load is assessed before and after root canal preparation, after intracanal medicament removal, and after final irrigation using droplet digital PCR.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patients aged between 18 and 65 years
* Being systemically healthy (ASA I or ASA II)
* Mandibular molar teeth with a radiographically detectable radiolucent lesion in the periapical region
* Willingness of the volunteer or their legal representative to participate in the study…
Inclusion Criteria:
* Patients aged between 18 and 65 years
* Being systemically healthy (ASA I or ASA II)
* Mandibular molar teeth with a radiographically detectable radiolucent lesion in the periapical region
* Willingness of the volunteer or their legal representative to participate in the study by signing the Informed Consent Form
Exclusion Criteria:
* Patients who have received antibiotics or corticosteroids within the last 3 months
* Patients with systemic diseases
* Teeth that cannot be properly isolated with a rubber dam
* Teeth with periodontal pockets \>4 mm and teeth with crown/root fractures
* Individuals who are undergoing or planning to start orthodontic treatment during the study period
* Pregnant or breastfeeding individuals
Contacts
No contact information available.
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