Clonal Hematopoiesis Chemotherapy and Radiation Effects Study

Recruiting Observational Study
Lung Cancer (Diagnosis) Osteochondroma Spitz Nevus Solid Cancers Breast Cancer Gastric (Stomach) Cancer Colorectal (Colon or Rectal) Cancer Sarcoma Ovarian Adenocarcinoma Uterine Adenocarcinoma Endometrial Adenocarcinoma Esophageal Adenocarcinoma Head and Neck Cancer Therapy-Related Acute Myeloid Leukemia Therapy-Related MDS Clonal Hematopoiesis of Indeterminate Potential (CHIP) Clonal Cytopenia of Undetermined Significance
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
5,000 (estimated)
Sponsor
Dana-Farber Cancer Institute · Other
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About This Trial
The goal of the Clonal Hematopoiesis Chemotherapy and Radiation Effects (CH CARE) Study is to understand how the presence or absence of clonal hematopoiesis (CH) influences outcomes in people receiving chemotherapy and radiation for solid cancers. The study will collect biospecimens and clinical information. These data will be used to define clinical and molecular features that predict the presen…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Participants to be included in this study include the following: * Adults age \>18 years * Diagnosed with solid malignancy (breast, ovarian, lung, gastric, colorectal, esophageal, uterine, head and neck, or sarcoma cancers) * Have a pending plan to receive chemotherapy or radi…
Contacts

Cindy Amaya Lopez, BA

857-215-1943

DFCICHCARESTUDY@DFCI.HARVARD.EDU

CONTACT

Jenna Beckwith, MPH

CONTACT