Safety and Feasibility of Next-Generation Dome Helmet (NGDH) for Focused Ultrasound Neuromodulation in Substance Use Disorder (SUD)

Recruiting N/A Interventional Study
Substance Use Disorder (SUD)
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 70
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
20 (estimated)
Sponsor
Sunnybrook Health Sciences Centre · Other
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About This Trial
The goal of this clinical trial is to evaluate the safety, feasibility, and preliminary clinical benefit of focused ultrasound (FUS) neuromodulation using the FUS Next Generation Dome Helmet (NGDH) in adults with treatment-resistant moderate-to-severe substance use disorder (SUD). The main questions it aims to answer are: Can FUS neuromodulation be safely delivered to the nucleus accumbens (NAc)…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Must be deemed to have capacity to provide informed consent (determined by the investigator) 2. Age between 18 to 70 (inclusive) 3. Diagnosis of SUD (cannabis, alcohol, ketamine, stimulant, opioid or nicotine/tobacco use disorder) in the moderate to severe range according to …
Contacts

Nir Lipsman, MD, PhD, FRCSC

(416)-480-6954

Nir.Lipsman@sunnybrook.ca

CONTACT

Anusha Baskaran, PhD

416-480-6100

CONTACT