A Study of Theranostic Pair PD-32766D/T in Participants With Carbonic Anhydrase IX Positive Clear Cell Renal Cell Carcinoma
Recruiting
Phase 1
Interventional Study
Clear Cell Renal Cell Carcinoma
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 1
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 60 (estimated)
- Sponsor
- PeptiDream Inc. · Industry
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About This Trial
This is an open-label, multicenter, Phase 1a/1b study evaluating the theranostic pair 64Cu-PD-32766 Injection (PD-32766D) and 225Ac-PD-32766 Injection (PD-32766T) in adult patients with relapsed or refractory Carbonic Anhydrase IX (CA9)-expressing clear cell renal cell carcinoma (ccRCC). The primary objective is to evaluate the safety and tolerability of PD-32766T, and to characterize its pharmaco…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Male or female participants aged ≥18 years.
2. Participants with confirmed diagnosis of ccRCC will be included based on the following characteristics:
* Histological confirmed locally advanced, unresectable, or metastatic ccRCC, after all available standard therapy.
* …
Contacts