CAR-T in Relapsed/Refractory Multiple Myeloma

Inclusion Criteria 1. Male and female participants of age 18 years and above. 2. Patients with a confirmed diagnosis of multiple myeloma according to IMWG diagnostic criteria. 3. Received at least 3 prior multiple myeloma treatment lines of therapy or are double refractory to an IMiD and PI (refractory multiple myeloma as defined by IMWG consensus criteria). Note: induction with or without hematopoietic stem cell transplant and with or without maintenance therapy is considered a single line of therapy. 4. Measurable disease at Screening as per IMWG criteria. 5. ECOG Performance Status grade of 0 to 2. 6. Adequate organ function: ANC/platelets thresholds (unless cytopenias attributable to MM), LVEF ≥45%, adequate oxygenation; hepatic/renal criteria specified in Section 10. 7. Negative pregnancy test for women of childbearing potential; agreement to effective contraception. 8. Patients giving written informed consent to participate in the study after a full understanding of the implications and constraints of the study protocol. 9. Understand the content of the ICF, and voluntarily sign the ICF (If the participant is unable to sign the ICF on their own due to illiteracy, an impartial witness is needed). 10. The subject can understand the research process and is willing and able to comply with all research proposals and other requirements of the study. 11. Willing and able to adhere to the prohibitions and restrictions specified in this protocol. Exclusion Criteria 1\. Patients who will meet any of the following criteria will not be eligible to participate in the study. 1. Prior treatment with CAR-T therapy directed at any target. Any therapy that is targeted to BCMA. 2. Known active, or prior history of central nervous system (CNS) involvement, or exhibits clinical signs of meningeal involvement of multiple myeloma. 3. Stroke or seizure within 6 months of signing the ICF. 4. Uncontrolled active infection, including uncontrolled bacterial or fungal infection; active uncontrolled HBV/HCV/HIV. 5. Clinically significant cardiac disease (e.g., NYHA III/IV, recent MI), or severe pulmonary disease. 6. Recent allogeneic HSCT with active GVHD or ongoing immunosuppression. 7. Pregnant or breast-feeding, or planning to become pregnant while enrolled in this study or within 1 year after receiving study treatment. 8. Any other circumstances that would impair the ability of the participant to receive or tolerate the planned treatment at the investigational site, to understand informed consent, or any condition for which, in the opinion of the investigator, participation would not be in the best interest of the participant (e.g., compromise the well-being) or that could prevent, limit, or confound the protocol-specified assessments. \- Exclusion Criteria: \-