Identifying Biomarkers Related to Opioid Use and Pain Response Following Traumatic Injury and Surgery
Recruiting
Observational Study
Opioid Use Disorder
Opioid Consumption
Persistent Opioid Use
Persistent Postsurgical Pain
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 100 (estimated)
- Sponsor
- University of California, San Diego · Other
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About This Trial
The mechanisms leading to opioid tolerance or dependence are not well understood and there are currently no biomarkers for predicting who is at risk for development of OUD. The purpose of this project is to support the feasibility of detecting a miRNA bio-behavioral signature of opioid misuse risk that will demonstrate improved predictive precision compared to current tools such as polygenic risk …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patients 18 years of age or older
* Patients admitted for traumatic injury at Hillcrest or Jacobs Medical Center or patients who will undergo the orthopedic (e.g., joint, spine), abdominal, breast, vascular (e.g., amputation), or thoracic surgery.
Exclusion Criteria:
* Patie…
Contacts