Pedunculopontine Nucleus Transcranial Ultrasound Stimulation as a Treatment of Freezing of Gait in Parkinson's Disease

Recruiting N/A Interventional Study
Parkinson Disease Freezing of Gait Symptoms in Parkinson Disease
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About This Trial
This study is investigating the use of transcranial ultrasound stimulation (TUS) on the Pedunculopontine nucleus (PPN) in changing freezing of gait in people with Parkinson's disease. The PPN is noted to be involved in voluntary movements, locomotion, and muscle tone. This will be assessed by patient-reported outcomes and analyzing the gait. The study will also investigate the effects of the stimu…
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Eligibility Criteria
Inclusion Criteria: * 18-90 years of age * Confirmed diagnosis of a movement disorder with Freezing of Gait * Stable dopaminergic medication dose for a minimum of 4 weeks Exclusion Criteria: * History of stroke or seizure * Comorbid dementia * Scored below 22 on the Montreal Cognitive Assessment …
Contacts

Julian Kwok

416-603-5800

julian.kwok@uhn.ca

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