Parkinson's Disease (PD)Alzheimer's Disease (AD) and Related DisordersOlder Adults (60 - 85 Years Old)
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 79
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
210 (estimated)
Sponsor
Emory University · Other
Who this trial is looking for
This trial is looking for older adults with Parkinson's Disease or Mild Cognitive Impairment. Participants will learn new movements set to music to see if it helps improve their condition.
Are You a Good Fit for This Trial?
Must not be takingAntipsychoticsOpioidsStimulantsChemotherapy medications
Rules you outActive central nervous system infectionsSeizure disordersHead injury with unconsciousness over 30 minutesIntracranial tumors
You may be able to join if
I am between 50 and 79 years old
I have Parkinson's Disease or Mild Cognitive Impairment
I do not have impaired decision-making capacity
I do less than 150 minutes of moderate exercise per week
You may not be able to join if
I have had an illness that required a hospital stay
I have uncontrolled heart failure
I have had a stroke in the past three years
I cannot perform the study procedures
I have severe arthritis or serious mobility problems
I take medications that affect my thinking
I have a psychotic disorder
I cannot provide informed consent
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
This study is being done to answer the question: Do people with Parkinson's benefit from a new stepping therapy, and how do people with Parkinson's best learn new steps and rhythms set to music? Researchers will also compare individuals with Parkinson's Disease with people with Mild Cognitive Impairment, and with people with neither of these conditions.
The purpose of this study is to identify pr…
This study is being done to answer the question: Do people with Parkinson's benefit from a new stepping therapy, and how do people with Parkinson's best learn new steps and rhythms set to music? Researchers will also compare individuals with Parkinson's Disease with people with Mild Cognitive Impairment, and with people with neither of these conditions.
The purpose of this study is to identify principles of human-music interactions to establish underlying guiding theories for application to music-based rehabilitation for older populations with neurodegenerative disease, leading to more refined and targeted music-based rhythmic movement therapies.
Trial Locations
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Eligibility Criteria
Inclusion Criteria for Young adults and adults with normal cognition (NC):
* 18 to 35 Years old
* Montreal Cognitive Assessment (MoCA) score of 26 to 30
Inclusion Criteria for Older Adults:
* 50 to 79 with or without MCI
* 50 to 79 years old with Parkinson's disease (PD), who do NOT have impaired…
Inclusion Criteria for Young adults and adults with normal cognition (NC):
* 18 to 35 Years old
* Montreal Cognitive Assessment (MoCA) score of 26 to 30
Inclusion Criteria for Older Adults:
* 50 to 79 with or without MCI
* 50 to 79 years old with Parkinson's disease (PD), who do NOT have impaired decision-making capacity
* Participants who achieve less than 150 minutes moderate or 75 minutes vigorous aerobic activity per week (as per the US Department of Health and Human Services (HHS)),
Exclusion Criteria for all groups:
* Acute medical illness requiring hospitalization;
* Uncontrolled congestive heart failure;
* History of stroke in the past three years;
* Inability to perform study procedures;
* Medical or physical conditions that would preclude participation (e.g., severe arthritis or mobility problems, uncontrolled hypertension or diabetes, renal failure, history of angina with activity);
* On medications that could adversely affect cognition, e.g., antipsychotics, opioids, stimulants, chemotherapy, and neurologic prescriptions to treat Multiple Sclerosis. When applicable, enrollment will be delayed until dosages are stable on e.g., Aricept, Namenda, anticholinesterase inhibitors, for at least 3 months
* Psychotic disorders
* Confounding neurologic conditions \[e.g., active central nervous system (CNS) opportunistic infections, seizure disorders, head injury with loss of consciousness \>30 minutes, intracranial neoplasms, stroke with neurological or neuropsychiatric sequelae\]
* Substance Use Disorder, Major Depressive Disorder, and Generalized Anxiety Disorder within six months of evaluation.
* Inability to provide informed consent
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