Zenagamtide Tablets for Weight Loss

AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight

Recruiting Phase 3 Interventional Study
Overweight Obesity
Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 3
Study type
Interventional
Purpose
Treatment
Participants needed
950 (estimated)
Sponsor
Novo Nordisk A/S · Industry
Who this trial is looking for

This trial is looking for adults with excess body weight who want to lose weight. Participants will take either zenagamtide or a placebo as a daily tablet. Which one you get is chosen by chance.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am 18 years old or older.
  • I am male or female.

You may not be able to join if

  • I have a glycated hemoglobin (HbA1c) of 6.5% or higher.
  • I have a history of type 1 or type 2 diabetes.
  • I have taken GLP-1 receptor agonists or similar treatments before.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial

The purpose of this clinical study is to find out if zenagamtide is safe and effective for treating people who have excess body weight. There are 2 study treatments in this study taken as oral tablets once a day. Participants will either get zenagamtide (the treatment being tested) or Placebo (treatment that has no active medicine in it). Which treatment participants get is decided by chance.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Male or female (sex at birth). * Age 18 and older (both inclusive) at time of signing the informed consent. Exclusion Criteria: * Glycated haemoglobin (HbA1c) more than or equal to (≥) 6.5% \[48 millimoles per mole (mmol/mol)\] as measured by the central laboratory at screen…
Contacts

Novo Nordisk

(+1) 866-867-7178

clinicaltrials@novonordisk.com

CONTACT