Endothelial Extracellular Vesicles as Biomarkers of Endothelial Activation in Pregnant Women With Hypertensive Disorders of Pregnancy
Recruiting
Observational Study
Hypertensive Disorder of Pregnancy
Gestational Hypertension
Preeclampsia
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About This Trial
Hypertensive disorders of pregnancy are associated with endothelial dysfunction and increased maternal and fetal morbidity. Endothelial extracellular vesicles (EEVs) have emerged as promising biomarkers of endothelial activation; however, their relationship with blood pressure and endothelial function during pregnancy remains incompletely understood. This observational case-control study aims to c…
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Eligibility Criteria
Inclusion Criteria:
* Pregnant women aged ≥18 years.
* Singleton pregnancy.
* Ability to provide written informed consent.
* Normotensive pregnancy or diagnosis of gestational hypertension or preeclampsia according to current clinical guidelines.
* Ability to comply with study procedures.
Exclusio…
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