A Longitudinal Natural History Study of OPA1-Associated Autosomal-Dominant Optic Atrophy
Recruiting
Observational Study
OPA1 Gene Mutation
Optic Atrophy, Autosomal Dominant
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Sex
- Any
- Study type
- Observational
- Participants needed
- 50 (estimated)
- Sponsor
- Ludwig-Maximilians - University of Munich · Other
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
This prospective, monocenter, non-interventional observational study investigates the natural history as well as the clinical and genetic spectrum of OPA1-associated autosomal dominant optic atrophy. Participants will undergo standardized ophthalmic and functional assessments, including visual acuity testing, visual field testing, color vision and contrast sensitivity testing, optical coherence to…
Trial Locations
Loading…
Loading trial locations…
Eligibility Criteria
Inclusion Criteria:
* Age 6 years or older
* Clinical diagnosis or clinical features consistent with optic atrophy
* Molecular genetic confirmation of a pathogenic or likely pathogenic variant in the OPA1 gene
* Ability of the participant, or the participant's parent or legal guardian, to understan…
Contacts