Serum Ferroptosis Biomarkers (GPX4, MDA) in Alopecia Areata
Recruiting
Observational Study
Alopecia Areata(AA)
Alopecia Areata
Alopecia Areata (& Ophiasis)
Alopecia
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 65
- Sex
- Any
- Study type
- Observational
- Participants needed
- 156 (estimated)
- Sponsor
- Istanbul Training and Research Hospital · Government
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About This Trial
This study aims to investigate the potential role of the ferroptosis pathway in the pathogenesis and clinical course of Alopecia Areata (AA). Serum concentrations of two key ferroptosis biomarkers-Glutathione Peroxidase 4 (GPX4), a primary antioxidant enzyme protecting against lipid peroxidation, and Malondialdehyde (MDA), a major end-product of lipid membrane damage-will be quantitatively measure…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patients aged between 18 and 65 years.
* Formally diagnosed with Alopecia Areata based on clinical and trichoscopic examination.
* Healthy volunteers with no personal or family history of alopecia or any systemic inflammatory/autoimmune conditions (for the healthy control grou…
Contacts