Eloralintide for Obesity and Overweight

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight

Recruiting Phase 1 Interventional Study
Obesity Overweight
Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 65
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Treatment
Participants needed
56 (estimated)
Sponsor
Eli Lilly and Company · Industry
Who this trial is looking for

This trial is looking for people who are overweight or obese to see how a medicine called Eloralintide affects stomach emptying. Participants will be involved for about 21 weeks and will have some overnight stays at a clinical research unit.

Are You a Good Fit for This Trial?
Rules you out Type 1 diabetesType 2 diabetesMajor depressive disorderSchizophreniaBipolar disorder

You may be able to join if

  • I have obesity or overweight
  • I have a body mass index (BMI) between 27.0 and 45.0
  • My body weight has not changed by more than 5% in the last 3 months

You may not be able to join if

  • I have been diagnosed with Type 1 or Type 2 diabetes
  • I have a fasting blood sugar level of 126 mg/dL or higher
  • I have a hemoglobin A1C of 6.5% or higher
  • I have a history of serious mental health issues in the last 2 years
  • I have taken certain diabetes medications in the last 60 days
  • I am considered at significant risk for suicide by a doctor

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial

The main purpose of this study is to find out how significantly Eloralintide slows stomach emptying in participants who are overweight or obese. For each participant, the study will last approximately 21 weeks and will include 2 overnight stays in the clinical research unit (CRU) lasting between 4 and 8 days. There will be 13 other visits.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Have overweight or obesity, but are otherwise overtly healthy. * Have a body mass index (BMI) within the range of 27.0 to 45.0 kilograms (kg)/square meter (m²), inclusive. * Have had a stable body weight, with less than 5 percent (%) change during the 3-month period prior to s…
Contacts

Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or

1-317-615-4559

LillyTrials@Lilly.com

CONTACT

Physicians interested in becoming principal investigators please contact

clinical_inquiry_hub@lilly.com

CONTACT