This study aims to evaluate how different doses of acute intermittent hypoxia (AIH) affect lower-limb strength, reaction time, and responsiveness in individuals with spinal cord injury (SCI). The objective is to identify the dose that most effectively improves motor output while also examining parameters that may account for variability in response.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Chronic Spinal Cord Injury (\>6 months)
* Motor incomplete SCI classified as AIS C or D
* Volitional ankle plantarflexion strength in at least one leg
Exclusion Criteria:
* Uncontrolled hypertension (outside 140/90 and 90/60)
* Concurrent medical illness
* Traumatic brain in…
Inclusion Criteria:
* Chronic Spinal Cord Injury (\>6 months)
* Motor incomplete SCI classified as AIS C or D
* Volitional ankle plantarflexion strength in at least one leg
Exclusion Criteria:
* Uncontrolled hypertension (outside 140/90 and 90/60)
* Concurrent medical illness
* Traumatic brain injury
* Cardiovascular complications
* Pulmonary complications
* Metabolic dysfunction
* Continued use of anti-spasticity medications
* Previously diagnosed obstructive sleep apnea
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