Palatoplasty Techniques Using PRF and Gentamicin-Loaded PRF in Cleft Palate

Recruiting N/A Interventional Study
Cleft Palate Unilateral Cleft Palate Bilateral Cleft Palate Complete Cleft Palat Incompelet Cleft Palate
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
3 Months – 18
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
90 (estimated)
Sponsor
Al-Thawra Modern General Hospital · Other
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About This Trial
This prospective, randomized controlled trial evaluates the clinical efficacy of autologous Platelet-Rich Fibrin (PRF) and Gentamicin-Loaded PRF as regenerative and antimicrobial biological adjuncts in primary palatoplasty. A total of 90 pediatric and adolescent patients with unilateral and bilateral complete and incomplete cleft palates will be assigned across three parallel treatment arms: stand…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Patients presenting with non-syndromic complete or incomplete unilateral or bilateral cleft palate. * Scheduled for primary palatoplasty. * Age within the specified study range. * Informed consent signed by parents or legal guardians. Exclusion Criteria: * Patients with asso…
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