Nebulizer vs Handheld Therapy for COPD

Nebulizer Versus Handheld Maintenance Therapy for Patients With COPD

Recruiting Phase 4 Interventional Study
COPD (Chronic Obstructive Pulmonary Disease) Chronic Obstructive Pulmonary Disease (COPD)
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
60 and older
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
120 (estimated)
Sponsor
COPD Foundation · Other
Who this trial is looking for

This trial is looking for patients with chronic obstructive pulmonary disease (COPD) who are not getting symptom relief from their current inhalers. Participants will switch from their inhaler to a nebulizer using similar medications to see if they feel better.

Are You a Good Fit for This Trial?
Must be taking LABA/LAMALABA/LAMA/ICS

You may be able to join if

  • I have smoked more than 10 pack-years.
  • I have been diagnosed with COPD.
  • I have been stable for the last 4 weeks.
  • My lung function tests showed FEV1 less than 50% predicted in the last year.
  • I have been using a single inhaler with certain medications for at least one month.

You may not be able to join if

  • I have dementia or cognitive impairment.
  • I have serious issues with my hands that affect my ability to use inhalers.
  • I have had a COPD flare-up in the last 2 months.
  • I currently have another lung disease like asthma.
  • I use a daily dose of Prednisone for my COPD.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial

Multi-site, randomized controlled trial to determine whether patients who report NO symptomatic benefit with their maintenance hand-held inhaler(s), benefit upon switching to nebulized therapy using comparable classes of medications.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * \> 10 pack-years smoking cigarettes * Diagnosis of COPD based on GOLD Criteria * Patients are clinically stable for the past 4 weeks * Prior Pulmonary function tests showing FEV1 \< 50% predicted (either 30 minutes post albuterol or within 2-4 hours after using their maintenan…
Contacts

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