Bayesian Optimization of DBS for Parkinson's Disease
Bayesian Optimization of DBS for Gait
Recruiting
Early Phase 1
Interventional Study
Parkinson Disease (PD)
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Early Phase 1
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 15 (estimated)
- Sponsor
- University of Minnesota · Other
Who this trial is looking for
This trial is looking for people with Parkinson's disease who have had deep brain stimulation (DBS) for at least three months. Participants will undergo measurements to help optimize their DBS settings for better walking.
Are You a Good Fit for This Trial?
You may be able to join if
- I have been diagnosed with Parkinson's disease
- I have DBS in the subthalamic nucleus or globus pallidus
- I have had my DBS leads implanted for at least 3 months
You may not be able to join if
- I cannot walk without my medication or stimulation
- My walking problems are due to something other than Parkinson's
- I have breaks or shorts in my DBS contacts
- My DBS battery is running low
- I am pregnant or breastfeeding
- I cannot give consent for myself
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
This project aims to establish the feasibility of Bayesian optimization for tuning deep brain stimulation (DBS) to treat gait symptoms in Parkinson's disease (PD) patients. Our primary question is: Can Bayesian optimization of DBS achieve reproducible results within a feasible number of gait measurements? PD patients will be enrolled who have DBS of the subthalamic nucleus (STN) or globus pallidus…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Diagnosis of Parkinson's Disease
* DBS in STN or GP (bilateral or unilateral)
* At least 3 months after lead implantation
Exclusion Criteria:
* Inability to walk in the off-med, off-stimulation condition (even with safety harness)
* Gait impaired significantly by a condition…
Contacts