Influenza Vaccine Effect on Provider Decision-Making

Inflammation and Medical Provider Attitudes, Cognition, and Treatment Decisions Study

Recruiting Phase 2 Interventional Study
Decision-Making Patient Care Treatment Decisions
Prior Safety Data This treatment has already been tested in at least one earlier human trial. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Health Services Research
Participants needed
210 (estimated)
Sponsor
University of Arkansas, Fayetteville · Other
Who this trial is looking for

This trial is looking for healthcare providers in emergency medicine or internal medicine. Participants will receive either a flu vaccine or a placebo and will complete assessments over two sessions to see how this affects their decision-making.

Are You a Good Fit for This Trial?
Must not be taking Tamiflu
Rules you out HIV/AIDSGraft vs. Host Disease

You may be able to join if

  • I am currently employed in emergency medicine or internal medicine
  • I am a resident, fellow, attending, or advanced practice provider
  • I can travel to the research site for sessions
  • I have not had an acute viral or bacterial infection in the last 14 days
  • I have not taken antiviral medication in the last 48 hours
  • I have not taken corticosteroids or immunosuppressants in the last 30 days

You may not be able to join if

  • I do not want to receive a flu vaccine as part of the study
  • I have received a flu vaccine this season already
  • I have had a prior allergic reaction to a flu vaccine
  • I am allergic to eggs or have had a bad reaction to an egg-derived vaccine
  • I am pregnant or suspect I might be pregnant
  • I have a congenital or acquired immunodeficiency
  • I have an active blood cancer
  • I have Type 1 diabetes

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

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About This Trial
This is a randomized, double-blind clinical trial involving emergency medicine and internal medicine healthcare providers as participants. The intervention involves the administration of the seasonal influenza vaccine or a saline placebo; this protocol is used in psychoneuro-immunology to simulate a state of mild illness. The primary aim is to examine whether acute inflammation induced by receivin…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Healthcare providers currently employed in emergency medicine or internal medicine * Must be one of the following: Resident, fellow, attending, or advanced practice provider (NP, PA) * Individual is able to travel to the research site for sessions * Has not had an acute viral …
Contacts

Anastasia Makhanova, PhD

479-575-8798

ammakhan@uark.edu

CONTACT