No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
240 (estimated)
Sponsor
Memorial Sloan Kettering Cancer Center · Other
Who this trial is looking for
This trial is looking for adults with advanced cancer who experience anxiety. Participants will try two different music-based therapies to see which helps reduce their anxiety and improve their sense of connection and coping skills.
Are You a Good Fit for This Trial?
You may be able to join if
I have been diagnosed with advanced cancer
I am currently receiving oncological treatment
I am at least 18 years old
I speak English or Spanish
I can move around and have a Karnofsky score of 60 or higher
I have an anxiety score of 8 or higher
I have experienced anxiety symptoms for at least 1 month
I have a cancer prognosis of more than 6 months
You may not be able to join if
I have been diagnosed with bipolar disorder or schizophrenia
I have a score of 10 or higher indicating dementia
I have received music therapy in the past 6 months
I am currently receiving psychotherapy
I have changed my scheduled anxiety medications in the past 4 weeks
I plan to change my scheduled anxiety medications during the study
I cannot access an internet-connected device
I cannot provide informed consent
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The researchers are doing this study to compare two different music-based treatment approaches and see if one may work better to reduce anxiety. The researchers will also study whether these music-based treatment approaches help people feel socially connected and change how they cope with anxiety, and whether these changes are linked to lower anxiety levels. Both approaches use music-based activit…
The researchers are doing this study to compare two different music-based treatment approaches and see if one may work better to reduce anxiety. The researchers will also study whether these music-based treatment approaches help people feel socially connected and change how they cope with anxiety, and whether these changes are linked to lower anxiety levels. Both approaches use music-based activities to treat anxiety. One of the approaches uses an artificial intelligence (AI)-powered song creation platform to write songs with a music therapist. The other approach involves music listening exercises and music-based discussions with research staff, during which you will learn about music culture and history.
Trial Locations
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Eligibility Criteria
Criteria:
* Patients must have a pathologically confirmed advanced cancer diagnosis: stage III or IV lung cancer; any stage pancreatic cancer, unresectable cholangiocarcinoma, unresectable liver cancer, unresectable ampullary or peri-ampullary cancer, or other stage IV gastrointestinal cancer; stag…
Criteria:
* Patients must have a pathologically confirmed advanced cancer diagnosis: stage III or IV lung cancer; any stage pancreatic cancer, unresectable cholangiocarcinoma, unresectable liver cancer, unresectable ampullary or peri-ampullary cancer, or other stage IV gastrointestinal cancer; stage III or IV ovarian or fallopian tube cancers or other stage IV gynecologic cancer; stage IV breast cancer; stage III testicular cancer or any stage IV genitourinary cancer; stage IV sarcoma; stage IV melanoma; stage IV endocrine cancer; lymphoma, myeloma, or leukemia
* Currently receiving oncological treatment
* Age ≥ 18; English speaking
* Ambulatory as indicated by a Karnofsky performance score of 60 or higher
* Score of 8 or higher on the Hospital Anxiety and Depression Scale (HADS) anxiety subscale
* Anxiety symptoms lasting for at least 1 month
* Greater than 6-month expected survival as judged by the treating oncologist or clinician on the study team
* No diagnosis of bipolar disorder, schizophrenia, or substance abuse
* Score of 10 or lower on Blessed Orientation-Memory-Concentration
* No prior receipt of music therapy within the past six months
* Not currently receiving any form of psychotherapy
* Concomitant Medications
* No initiation or change in scheduled anxiety medications (e.g., anxiolytics, sedatives, hypnotics, antidepressants) within the past 4 weeks
* Initiation or change in PRN anxiety medications are allowed within the past 4 weeks
* No plan to initiate or change scheduled anxiety medications during the study
* Initiation or change in PRN anxiety medications are allowed during the study
* Access to an internet-connected device
* Able to provide informed consent
* Willing to adhere to study procedures, including randomization, session attendance, and completion of assessments
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