The Use of Risk Prediction to Identify Patients at Risk for Chronic Kidney Disease: Patient and Provider Interventions for Patients at High Risk for Chronic Kidney Disease
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
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At a Glance
Age
18 – 80
Sex
Any
Study type
Interventional
Purpose
Screening
Participants needed
1,500 (estimated)
Sponsor
Kaiser Permanente · Other
Who this trial is looking for
This trial is looking for adults at high risk for chronic kidney disease. Participants will be notified about their risk and have follow-up testing for kidney disease.
Are You a Good Fit for This Trial?
You may be able to join if
I am aged 18 to 80 years old
I speak English or Spanish
I have been identified as high risk for kidney disease
I have had health plan coverage for at least 12 months
You may not be able to join if
I am currently on hospice care
I have conditions indicating end of life such as metastatic cancer or dialysis
I do not speak English or Spanish
I am pregnant
I have had both eGFR and uACR tests within the last 12 months
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
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This prospective, cluster-randomized trial is structured as a pragmatic study, embedding the outreach intervention within routine clinical workflows. The intervention reflects real-world provider-patient communication methods. The primary research aim is to evaluate, under typical practice conditions, whether structured notification strategies improve follow-up screening.
We will evaluate whether…
This prospective, cluster-randomized trial is structured as a pragmatic study, embedding the outreach intervention within routine clinical workflows. The intervention reflects real-world provider-patient communication methods. The primary research aim is to evaluate, under typical practice conditions, whether structured notification strategies improve follow-up screening.
We will evaluate whether targeted provider and patient-directed communication increases completion of CKD disease lab testing (eGFR and uACR) among individuals identified as being at risk for having CKD based on the model developed in in Phase 1. We will identify up to 1,000 patients with high risk of having CKD. All patients' primary care providers (PCPs) will receive a message notifying them of patients' elevated risk status and the recommendation for CKD testing per standard practice. Additionally, we will randomly allocate providers whose patients will receive letters ( \~n=500 patients) and providers whose patients will receive a phone call ( \~n=250 patients).
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* At high risk for CKD as determined by CKD model developed in Phase 1
* Age 18-80 as of date of data pull
* At least 12 months of health plan coverage
* Speaks English or Spanish
* We will include both paneled and unpaneled patients
Exclusion criteria:
* On the research exclu…
Inclusion Criteria:
* At high risk for CKD as determined by CKD model developed in Phase 1
* Age 18-80 as of date of data pull
* At least 12 months of health plan coverage
* Speaks English or Spanish
* We will include both paneled and unpaneled patients
Exclusion criteria:
* On the research exclusion list between 1/1/2013 and date of the data pull
* On hospice, or have conditions that indicate end of life (metastatic cancer, on dialysis, etc.)
* Non-English / non-Spanish speaking (those who are excluded from the intervention arm solely due to language barriers will be reported to the IRB at continuing review).
* Pregnant patients.
* Patients who have a completed both the eGFR and uACR within the 12 months prior to the date of cohort identification.
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