No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
15 – 75
Sex
Any
Study type
Observational
Participants needed
3,200 (estimated)
Sponsor
University of Michigan · Other
Who this trial is looking for
This trial is looking for overweight and obese individuals who want to learn about weight management strategies. Participants can choose standard care or explore different studies related to nutrition and medication for weight loss.
Are You a Good Fit for This Trial?
Rules you outInherited lipid metabolism disordersGastrointestinal diseaseEnd stage renal diseaseEnd stage liver diseaseAutoimmune disordersPrior bariatric surgeryUnstable anginaSubstance abuse history
You may be able to join if
I am over 20 years old
I have a BMI of 27 or higher, or between 17 and 27
I am willing to provide written consent to join the trial
You may not be able to join if
I have had a history of cancer in the last 5 years
I am HIV positive
I have a solid organ transplant
I am pregnant or breastfeeding
I have uncontrolled thyroid disease
I have a history of severe mental health issues
I have had significant weight changes in the past 3 months
I am unwilling or unable to consent for the study
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The Investigational Weight Management Clinic now entitled the Weight Management Program at the University of Michigan was created to identify strategies that will result in cost-effective, long term weight management for overweight and obese individuals. The driving hypothesis of the clinic is that the 'one size fits all' philosophy is untenable with a complex disease such as obesity. The clinic w…
The Investigational Weight Management Clinic now entitled the Weight Management Program at the University of Michigan was created to identify strategies that will result in cost-effective, long term weight management for overweight and obese individuals. The driving hypothesis of the clinic is that the 'one size fits all' philosophy is untenable with a complex disease such as obesity. The clinic will serve as a portal for patients to choose standard clinical care or to explore alternatives from a variety of clinical studies offered through the clinic. These studies will include further investigations into nutrition, the biological basis of weight and weight management and protocols using approved and experimental pharmaceuticals as well as technologies that aid in self-management of weight.
Trial Locations
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City
State
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Status
Eligibility Criteria
Inclusion Criteria:
* Obese males and females: age \>20 years; Obese population defined as BMI \> or = 27 kg/m2
* Lean population BMI \< 27 but \> 17 kg/m2
* Able and willing to provide written informed consent for the trial
Exclusion Criteria:
* Evidence of inherited disorders of lipid metabolis…
Inclusion Criteria:
* Obese males and females: age \>20 years; Obese population defined as BMI \> or = 27 kg/m2
* Lean population BMI \< 27 but \> 17 kg/m2
* Able and willing to provide written informed consent for the trial
Exclusion Criteria:
* Evidence of inherited disorders of lipid metabolism.
* History of Cancer within the last 5 years
* Human immunodeficiency virus (HIV) antibody positive.
* Patients with solid organ transplants.
* Participation in any other clinical trial within 90 days of entry into this trial.
* Pregnant or lactating females.
* Uncontrolled thyroid disease
* Unstable angina or NY heart association class II failure or above
* Gastrointestinal disease specifically GI motility disorders
* Unstable neuropsychiatric disease including major depression/anxiety, eating disorder such as binge eating, bulimia or anorexia
* End stage renal or hepatic disease
* Autoimmune disorders (e.g. SLE)
* Body weight fluctuation of more than 5 kg in the previous 3 months
* Prior bariatric surgery
* A history or current alcohol/substance abuse and change in smoking habits or cessation in the past 6 months.
* Women of childbearing age must use a reliable form of contraception.
* Any medical condition, which in the opinion of the investigator would make the patient unsuitable for recruitment, or could interfere with the patient participating in or completing the protocol.
* Unwilling or unable to consent for the study.
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