41 Recruiting Trials

Clinical Trials
for Obesity in Michigan

41 clinical trials for Obesity are currently recruiting participants at study sites in Michigan. Study-related care is provided at no cost.

41
Recruiting trials
38
Study sites
18
Cities
31
Industry-sponsored
7
Phase 2
24
Phase 3

Obesity clinical trials in Michigan: what to expect

Obesity trials are among the most actively recruiting studies in the United States right now. Most test medicines from the GLP-1 family (the class that includes semaglutide and tirzepatide) or newer compounds that work on the same appetite and blood-sugar pathways, often in people who also have high blood pressure, sleep apnea, knee osteoarthritis or prediabetes. A smaller number study structured diet and exercise programs, devices, or weight-loss surgery.

In Michigan, recruiting obesity studies are concentrated in Ann Arbor, Southfield, Troy and Farmington Hills, with sites in 14 other cities. 31 of the 41 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who obesity trials usually look for

Nearly every study sets a body mass index (BMI) threshold, most often 30 or higher, or 27 or higher when you also have a weight-related condition. Many ask that your weight has been stable for the last three months and that you are not currently using a prescription weight-loss drug. Age limits of 18 to 75 are common. Pregnancy, a history of pancreatitis or certain thyroid cancers, and bariatric surgery within the last few years are the exclusions that come up most.

If you have type 2 diabetes, look for trials that name it: some obesity studies exclude diabetes, while others are designed specifically for people who have both.

What taking part involves

A screening visit with a physical exam, blood work and an ECG usually comes first. Drug trials then run for six months to two years, with study visits every few weeks at the start and every one to three months later on. Most GLP-1 studies use a once-weekly injection you give yourself at home; many are placebo-controlled, meaning some participants receive an inactive version for part or all of the study, and you are told that before you agree to join. Study medication, visits and tests are provided at no cost, and most trials pay a stipend for time and travel.

Questions worth asking the study team

Whether there is a placebo group and how long it lasts; whether you can continue the medicine after the study ends; how many visits are required and how far the site is from you; and what happens if you need to stop early. Sites answer these every day and a ten-minute phone screen is the normal next step.

Showing 20 of 41 recruiting Obesity trials in Michigan

A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
PHASE3 Canoga Park, California +4 sites NCT07595549
This trial is looking for adults with overweight or obesity who may also have type 2 diabetes. Participants will get either a shot of the study medicine, berobenatide, or a placebo that doesn't contain any medicine. The study lasts for about 20 months and involves regular visits to check on health and weight.
Recruiting
Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS)
PHASE3 Tucson, Arizona +4 sites NCT07817875
This trial is looking for children aged 6 to less than 12 years who have obesity. Participants will try a new treatment along with healthy lifestyle changes for about two years.
Recruiting
A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)
PHASE3 Tucson, Arizona +4 sites NCT06672549
This trial is looking for teens aged 12 to under 18 who are struggling with obesity or being overweight. Participants must have tried losing weight before but were unsuccessful.
Recruiting
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)
PHASE3 Anniston, Alabama +4 sites NCT07684235
This trial is looking for individuals with obesity or overweight who have completed a previous trial. Participants will receive maridebart cafraglutide and be monitored for safety and effectiveness over a longer period.
Recruiting
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
PHASE3 Birmingham, Alabama +4 sites NCT07564414
This trial is looking for people with obesity, with or without type 2 diabetes, who want to lose weight. Participants will be assigned by chance to receive either CagriSema or semaglutide for about 83 weeks.
Recruiting
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
PHASE3 Tuscaloosa, Alabama +4 sites NCT07321886
This trial is looking for adults who are overweight or have obesity but do not have type 2 diabetes. Participants will take eloralintide for a main phase lasting about 75 weeks, with an option to continue for another 2 years if they have prediabetes.
Recruiting
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes
PHASE3 Birmingham, Alabama +4 sites NCT07743450
This trial is looking for adults with obesity or overweight who have type 2 diabetes. Participants will take a daily oral medication to see how well it works and how safe it is over time.
Recruiting
Efficacy and Safety of Ribupatide Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes
PHASE3 Glendale, Arizona +4 sites NCT07284979
This trial is looking for individuals living with obesity who have struggled to lose weight through diet and exercise. Participants will receive a weekly injection of ribupatide and will be compared to those receiving semaglutide or a placebo.
Recruiting
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
PHASE3 Alexander City, Alabama +4 sites NCT07567001
This trial is looking for individuals with heart failure who are also obese. Participants will receive either an injection of NNC0487-0111 or a placebo once a week to see how well it works and how safe it is.
Recruiting
AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
PHASE3 Escondido, California +4 sites NCT07509307
This trial is looking for people with excess weight and knee osteoarthritis. Participants will receive an injection either of the study medicine or a placebo once a week for a set period of time.
Recruiting
Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)
PHASE3 Birmingham, Alabama +4 sites NCT07654361
This trial is looking for adults with obesity or overweight who have health problems related to their weight. Participants will take a daily medication called aleniglipron for at least 76 weeks while following a reduced-calorie diet and increasing physical activity.
Recruiting
A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
PHASE2 Chandler, Arizona +4 sites NCT06143956
This trial is looking for adults who are overweight or have obesity to test different weight management treatments. Participants will be evaluated to see if they can safely join the trial.
Recruiting
Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)
PHASE3 Pelham, Alabama +4 sites NCT07575399
This trial is looking for adults who are overweight or obese and have been using a specific medication for weight loss. Participants will switch to taking maridebart cafraglutide and be monitored for effects and side effects.
Recruiting
A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight
PHASE3 Fairhope, Alabama +4 sites NCT07784270
This trial is looking for adults with type 2 diabetes and obesity or being overweight. Participants will take AZD6234 or a placebo for 68 weeks to see how it affects their body weight.
Recruiting
Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes
PHASE3 Cullman, Alabama +4 sites NCT07284901
This trial is looking for people with obesity or overweight who also have type 2 diabetes. Participants will receive a weekly injection of ribupatide to see how it affects their weight and blood sugar levels.
Recruiting
A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus
PHASE3 Dothan, Alabama +4 sites NCT07784725
This trial is looking for adults with obesity or overweight who have tried to lose weight before. Participants will take AZD6234 or a placebo for 68 weeks to see how it affects weight change.
Recruiting
Michigan Weight Navigation Program (MiWeigh) Study
NA Ann Arbor, Michigan NCT07465341
This trial is looking for people with obesity who want to lose weight. Participants will either join the MiWeigh program or receive basic weight loss information. They will have virtual visits and report their weight weekly if they are in the program group.
Recruiting
Exercise Effects on Adipose Tissue Structure and Function
NA Ann Arbor, Michigan NCT04812314
This trial is looking for adults aged 18-40 who are overweight and don't exercise regularly. Participants will go through a weight loss program and then follow a high-calorie diet while being tested for changes in their metabolism.
Recruiting
Recruiting

Where the Obesity studies are in Michigan

  • University of Michigan, Ann Arbor7 trials
  • Arcturus Healthcare , PLC, Troy Internal Medicine Research Division, Troy6 trials
  • Headlands Research - Detroit, Southfield3 trials
  • Aa Mrc Llc, Flint2 trials
  • Great Lakes Research Institute, Southfield2 trials
  • Helen Devos Childrens' Hospital - PIN, Grand Rapids2 trials

Counts are recruiting studies listing at least one site in Michigan, from ClinicalTrials.gov, refreshed every two days.

Obesity clinical trials in Michigan: common questions

How many Obesity clinical trials are recruiting in Michigan?
TrialFinder currently lists 41 recruiting Obesity clinical trials with study sites in Michigan. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Obesity clinical trials located in Michigan?
Study sites for the Obesity trials listed on this page include Ann Arbor. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Obesity clinical trial in Michigan?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Obesity trials in Michigan also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Obesity clinical trial in Michigan?
Each study sets its own criteria based on age, Obesity diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need a BMI over 30 to join an obesity clinical trial?
Most adult obesity trials require a BMI of 30 or higher, or 27 or higher if you also have a weight-related condition such as high blood pressure, prediabetes or sleep apnea. Each trial page lists its exact threshold.
Are obesity trial participants paid?
Study medication, visits and tests are provided free, and most obesity trials pay a stipend per visit for time and travel. The amount is set by each study and told to you before you enroll; it is never contingent on finishing the study.
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Obesity trials study GLP-1 receptor agonists, bariatric procedures, behavioural interventions, and combination weight-loss therapies in adults and adolescents.

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