31 Recruiting Trials

Clinical Trials
for Obesity in Indiana

31 clinical trials for Obesity are currently recruiting participants at study sites in Indiana. Study-related care is provided at no cost.

31
Recruiting trials
35
Study sites
12
Cities
23
Industry-sponsored
3
Phase 2
19
Phase 3

Obesity clinical trials in Indiana: what to expect

Obesity trials are among the most actively recruiting studies in the United States right now. Most test medicines from the GLP-1 family (the class that includes semaglutide and tirzepatide) or newer compounds that work on the same appetite and blood-sugar pathways, often in people who also have high blood pressure, sleep apnea, knee osteoarthritis or prediabetes. A smaller number study structured diet and exercise programs, devices, or weight-loss surgery.

In Indiana, recruiting obesity studies are concentrated in Indianapolis, Evansville, Valparaiso and Muncie, with sites in 8 other cities. 23 of the 31 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who obesity trials usually look for

Nearly every study sets a body mass index (BMI) threshold, most often 30 or higher, or 27 or higher when you also have a weight-related condition. Many ask that your weight has been stable for the last three months and that you are not currently using a prescription weight-loss drug. Age limits of 18 to 75 are common. Pregnancy, a history of pancreatitis or certain thyroid cancers, and bariatric surgery within the last few years are the exclusions that come up most.

If you have type 2 diabetes, look for trials that name it: some obesity studies exclude diabetes, while others are designed specifically for people who have both.

What taking part involves

A screening visit with a physical exam, blood work and an ECG usually comes first. Drug trials then run for six months to two years, with study visits every few weeks at the start and every one to three months later on. Most GLP-1 studies use a once-weekly injection you give yourself at home; many are placebo-controlled, meaning some participants receive an inactive version for part or all of the study, and you are told that before you agree to join. Study medication, visits and tests are provided at no cost, and most trials pay a stipend for time and travel.

Questions worth asking the study team

Whether there is a placebo group and how long it lasts; whether you can continue the medicine after the study ends; how many visits are required and how far the site is from you; and what happens if you need to stop early. Sites answer these every day and a ten-minute phone screen is the normal next step.

Showing 20 of 31 recruiting Obesity trials in Indiana

A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
PHASE3 Canoga Park, California +4 sites NCT07595549
This trial is looking for adults with overweight or obesity who may also have type 2 diabetes. Participants will get either a shot of the study medicine, berobenatide, or a placebo that doesn't contain any medicine. The study lasts for about 20 months and involves regular visits to check on health and weight.
Recruiting
Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS)
PHASE3 Tucson, Arizona +4 sites NCT07817875
This trial is looking for children aged 6 to less than 12 years who have obesity. Participants will try a new treatment along with healthy lifestyle changes for about two years.
Recruiting
A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)
PHASE3 Tucson, Arizona +4 sites NCT06672549
This trial is looking for teens aged 12 to under 18 who are struggling with obesity or being overweight. Participants must have tried losing weight before but were unsuccessful.
Recruiting
A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)
PHASE3 Los Angeles, California +4 sites NCT06439277
This trial is looking for adolescents with obesity and related health issues. Participants will take tirzepatide and continue healthy eating and exercise over about 76 weeks.
Recruiting
AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight
PHASE3 Indianapolis, Indiana +4 sites NCT07339423
This trial is looking for people with excess body weight who want to lose weight. Participants will receive either the treatment NNC0487-0111 or a placebo injection once a week.
Recruiting
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes
PHASE3 Birmingham, Alabama +4 sites NCT07743450
This trial is looking for adults with obesity or overweight who have type 2 diabetes. Participants will take a daily oral medication to see how well it works and how safe it is over time.
Recruiting
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities
PHASE3 Birmingham, Alabama +4 sites NCT07743463
This trial is looking for adults who are overweight or obese and have weight-related health problems. Participants will take a daily pill for the study to see how well it helps with weight management and its safety.
Recruiting
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
PHASE3 Alexander City, Alabama +4 sites NCT07567001
This trial is looking for individuals with heart failure who are also obese. Participants will receive either an injection of NNC0487-0111 or a placebo once a week to see how well it works and how safe it is.
Recruiting
Recruiting
Recruiting
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
PHASE3 Daphne, Alabama +4 sites NCT07037433
This trial is looking for adults with heart disease and obesity. Participants will receive either maridebart cafraglutide or a placebo while continuing usual care.
Recruiting
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
PHASE3 Birmingham, Alabama +4 sites NCT07282600
This trial is looking for people with obesity or overweight who also have type 2 diabetes. Participants will take eloralintide or a placebo for about 75 weeks to see if it helps with weight loss.
Recruiting
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
PHASE3 Escondido, California +4 sites NCT07253285
This trial is looking for children and teens aged 8 to 17 who have excess body weight. Participants will receive either a new drug or a placebo and will be followed for up to 4 years. There may be side effects from the treatments.
Recruiting
A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide
PHASE3 Lancaster, California +4 sites NCT07668414
This trial is looking for adults who are overweight or obese to test how well a new medicine, zenagamtide, helps with weight loss compared to another medicine called semaglutide. Participants will need to meet certain health requirements to join.
Recruiting
AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight
PHASE3 Anniston, Alabama +4 sites NCT07720271
This trial is looking for adults with excess body weight who want to lose weight. Participants will take either zenagamtide or a placebo as a daily tablet. Which one you get is chosen by chance.
Recruiting
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
PHASE3 Birmingham, Alabama +4 sites NCT07037459
This trial is looking for adults with heart failure and obesity. Participants will take a new treatment along with their usual heart failure care to see if it helps reduce heart failure problems.
Recruiting
A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight
PHASE3 Indianapolis, Indiana +4 sites NCT07745504
This trial is looking for adults with excess body weight who want to lose weight. If you join, you may receive either the study medicine cagrilintide or a placebo. The study will last about 9 months.
Recruiting
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
PHASE3 Mobile, Alabama +4 sites NCT07353931
This trial is looking for adults who are at least 50 years old and have knee pain from osteoarthritis, as well as being overweight or obese. It’s important that they haven't had a recent heart issue or surgery for weight loss, and they shouldn’t have diabetes. Participants also need to have tried losing weight through diet without success.
Recruiting

Where the Obesity studies are in Indiana

  • Midwest Inst For Clin Res, Indianapolis4 trials
  • Indiana University Health University Hospital, Indianapolis3 trials
  • Cardiovascular Research of Northwest Indiana LLC, Munster2 trials
  • Gastroenterology Health Partners, New Albany2 trials
  • Health Professions Building, Muncie2 trials
  • Indiana University, Indianapolis2 trials

Counts are recruiting studies listing at least one site in Indiana, from ClinicalTrials.gov, refreshed every two days.

Obesity clinical trials in Indiana: common questions

How many Obesity clinical trials are recruiting in Indiana?
TrialFinder currently lists 31 recruiting Obesity clinical trials with study sites in Indiana. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Obesity clinical trials located in Indiana?
Study sites for the Obesity trials listed on this page include Indianapolis, Muncie, Bloomington. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Obesity clinical trial in Indiana?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Obesity trials in Indiana also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Obesity clinical trial in Indiana?
Each study sets its own criteria based on age, Obesity diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need a BMI over 30 to join an obesity clinical trial?
Most adult obesity trials require a BMI of 30 or higher, or 27 or higher if you also have a weight-related condition such as high blood pressure, prediabetes or sleep apnea. Each trial page lists its exact threshold.
Are obesity trial participants paid?
Study medication, visits and tests are provided free, and most obesity trials pay a stipend per visit for time and travel. The amount is set by each study and told to you before you enroll; it is never contingent on finishing the study.
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Obesity trials study GLP-1 receptor agonists, bariatric procedures, behavioural interventions, and combination weight-loss therapies in adults and adolescents.

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