22 Recruiting Trials

Clinical Trials
for Obesity in Rhode Island

22 clinical trials for Obesity are currently recruiting participants at study sites in Rhode Island. Study-related care is provided at no cost.

22
Recruiting trials
14
Study sites
4
Cities
11
Industry-sponsored
1
Phase 2
11
Phase 3

Obesity clinical trials in Rhode Island: what to expect

Obesity trials are among the most actively recruiting studies in the United States right now. Most test medicines from the GLP-1 family (the class that includes semaglutide and tirzepatide) or newer compounds that work on the same appetite and blood-sugar pathways, often in people who also have high blood pressure, sleep apnea, knee osteoarthritis or prediabetes. A smaller number study structured diet and exercise programs, devices, or weight-loss surgery.

In Rhode Island, recruiting obesity studies are concentrated in Providence, East Greenwich, Cumberland and East Providence. 11 of the 22 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who obesity trials usually look for

Nearly every study sets a body mass index (BMI) threshold, most often 30 or higher, or 27 or higher when you also have a weight-related condition. Many ask that your weight has been stable for the last three months and that you are not currently using a prescription weight-loss drug. Age limits of 18 to 75 are common. Pregnancy, a history of pancreatitis or certain thyroid cancers, and bariatric surgery within the last few years are the exclusions that come up most.

If you have type 2 diabetes, look for trials that name it: some obesity studies exclude diabetes, while others are designed specifically for people who have both.

What taking part involves

A screening visit with a physical exam, blood work and an ECG usually comes first. Drug trials then run for six months to two years, with study visits every few weeks at the start and every one to three months later on. Most GLP-1 studies use a once-weekly injection you give yourself at home; many are placebo-controlled, meaning some participants receive an inactive version for part or all of the study, and you are told that before you agree to join. Study medication, visits and tests are provided at no cost, and most trials pay a stipend for time and travel.

Questions worth asking the study team

Whether there is a placebo group and how long it lasts; whether you can continue the medicine after the study ends; how many visits are required and how far the site is from you; and what happens if you need to stop early. Sites answer these every day and a ten-minute phone screen is the normal next step.

Showing 20 of 22 recruiting Obesity trials in Rhode Island

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)
PHASE3 Gilbert, Arizona +4 sites NCT07684144
This trial is looking for people with obesity and type 2 diabetes who have completed a previous study. Participants will take a medication to see how it works over a longer time period, while following specific rules during the trial.
Recruiting
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)
PHASE3 Anniston, Alabama +4 sites NCT07684235
This trial is looking for individuals with obesity or overweight who have completed a previous trial. Participants will receive maridebart cafraglutide and be monitored for safety and effectiveness over a longer period.
Recruiting
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
PHASE3 Birmingham, Alabama +4 sites NCT07564414
This trial is looking for people with obesity, with or without type 2 diabetes, who want to lose weight. Participants will be assigned by chance to receive either CagriSema or semaglutide for about 83 weeks.
Recruiting
AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight
PHASE3 Miramar, Florida +4 sites NCT07339423
This trial is looking for people with excess body weight who want to lose weight. Participants will receive either the treatment NNC0487-0111 or a placebo injection once a week.
Recruiting
Efficacy and Safety of Ribupatide Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes
PHASE3 Glendale, Arizona +4 sites NCT07284979
This trial is looking for individuals living with obesity who have struggled to lose weight through diet and exercise. Participants will receive a weekly injection of ribupatide and will be compared to those receiving semaglutide or a placebo.
Recruiting
Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes
PHASE3 Cullman, Alabama +4 sites NCT07284901
This trial is looking for people with obesity or overweight who also have type 2 diabetes. Participants will receive a weekly injection of ribupatide to see how it affects their weight and blood sugar levels.
Recruiting
Brain and Behavior Influences on Obesity Development From Infancy Through Childhood
NA Providence, Rhode Island +3 sites NCT06861868
This trial is looking for children aged 7-12 years who have no food allergies. Participants will help researchers understand why some kids become obese by sharing information about their eating habits, genetics, and brain development.
Recruiting
Cognitive Strategies for Weight Loss
NA Providence, Rhode Island NCT05799846
This trial is looking for adults with obesity who want to lose weight. Participation involves being assigned to one of three online weight loss programs and completing assessments over 18 months.
Recruiting
Optimizing an Online Behavioral Weight Loss Intervention and Novel Culturally Tailored Components for Sexual Minority Women
NA Providence, Rhode Island NCT05775497
This trial is looking for women who identify as a sexual minority and want to lose weight. Participants will join an online program designed to help with weight loss over 12 weeks.
Recruiting
Control Systems Engineering for Weight Loss Maintenance
PHASE2 Providence, Rhode Island NCT06244888
This trial is looking for people who are overweight or obese and want to maintain weight loss. Participants will undergo a behavioral treatment to lose weight, followed by surveys to help understand weight maintenance.
Recruiting
Weight Management Intervention in College: A Pilot
NA Providence, Rhode Island NCT06994923
Recruiting
Remote Approaches for Optimizing Weight Loss (Elevate Weight Loss Trial)
NA Providence, Rhode Island NCT06875622
This trial is looking for individuals with overweight or obesity who want to lose weight. Participants will take part in a 12-month program that helps with weight loss through different methods and support options.
Recruiting
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
PHASE3 Daphne, Alabama +4 sites NCT07037433
This trial is looking for adults with heart disease and obesity. Participants will receive either maridebart cafraglutide or a placebo while continuing usual care.
Recruiting
AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight
PHASE3 Anniston, Alabama +4 sites NCT07720271
This trial is looking for adults with excess body weight who want to lose weight. Participants will take either zenagamtide or a placebo as a daily tablet. Which one you get is chosen by chance.
Recruiting
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
PHASE3 Dothan, Alabama +4 sites NCT06937086
This trial is looking for adults with moderate to severe ulcerative colitis and obesity or overweight. Participants will receive a treatment for about a year to see if it helps with their symptoms and weight loss.
Recruiting
Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
PHASE3 Dothan, Alabama +4 sites NCT06937099
This trial is looking for adults who have moderate to severe Crohn's disease and are either overweight or obese. They should also have some weight-related health issues, like high blood pressure or diabetes. However, if you have certain other conditions, like severe infections or have had recent surgeries, you wouldn’t be able to participate.
Recruiting
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
PHASE3 Birmingham, Alabama +4 sites NCT07667803
This trial is looking for adults with obesity or overweight. Participants will take a medication called elecoglipron while following a diet and exercise program to help manage their weight.
Recruiting
Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes
NA Providence, Rhode Island +4 sites NCT05124808
This trial is looking for overweight and obese pregnant women who have been diagnosed with gestational diabetes. Participants will compare different approaches to blood sugar control during pregnancy.
Recruiting

Where the Obesity studies are in Rhode Island

  • Clinical Res Collaborative, Cumberland3 trials
  • Velocity Clinical Research - Providence, East Greenwich3 trials
  • Weight Control and Diabetes Research Center, Providence3 trials
  • Kailera Clinical Site, East Greenwich2 trials
  • University Gastroenterology, Providence2 trials
  • Brown University, Providence1 trial

Counts are recruiting studies listing at least one site in Rhode Island, from ClinicalTrials.gov, refreshed every two days.

Obesity clinical trials in Rhode Island: common questions

How many Obesity clinical trials are recruiting in Rhode Island?
TrialFinder currently lists 22 recruiting Obesity clinical trials with study sites in Rhode Island. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Obesity clinical trials located in Rhode Island?
Study sites for the Obesity trials listed on this page include Providence. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Obesity clinical trial in Rhode Island?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Obesity trials in Rhode Island also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Obesity clinical trial in Rhode Island?
Each study sets its own criteria based on age, Obesity diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need a BMI over 30 to join an obesity clinical trial?
Most adult obesity trials require a BMI of 30 or higher, or 27 or higher if you also have a weight-related condition such as high blood pressure, prediabetes or sleep apnea. Each trial page lists its exact threshold.
Are obesity trial participants paid?
Study medication, visits and tests are provided free, and most obesity trials pay a stipend per visit for time and travel. The amount is set by each study and told to you before you enroll; it is never contingent on finishing the study.
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Obesity trials study GLP-1 receptor agonists, bariatric procedures, behavioural interventions, and combination weight-loss therapies in adults and adolescents.

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