No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 70
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
360 (estimated)
Sponsor
The Miriam Hospital · Other
Who this trial is looking for
This trial is looking for adults with obesity who want to lose weight. Participation involves being assigned to one of three online weight loss programs and completing assessments over 18 months.
Are You a Good Fit for This Trial?
Must not be takingWeight loss medications
Rules you outNeurological conditionsPsychiatric conditions
You may be able to join if
I am between 18 and 70 years old.
I have a BMI between 25 and 45.
I have regular access to the Internet.
You may not be able to join if
I am currently enrolled in a weight loss program.
I am taking weight loss medications.
I have had bariatric surgery or plan to have it in the next 18 months.
I am pregnant, nursing, or planning to become pregnant in the next 18 months.
I plan to move outside the area in the next 18 months.
I have a medical condition that means I shouldn't lose weight.
I have neurological or psychiatric conditions like schizophrenia or bipolar disorder.
I cannot attend assessments in Providence, RI.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The goal of this clinical trial is to compare weight change and other related outcomes associated with three different behavioral weight loss interventions (STANDARD Behavioral, PREVENT, and PROMOTE) in adults with obesity. The main questions it aims to answer are:
* Which of the three Internet-delivered weight loss programs results in the greatest weight loss?
* How do key weight-related behavio…
The goal of this clinical trial is to compare weight change and other related outcomes associated with three different behavioral weight loss interventions (STANDARD Behavioral, PREVENT, and PROMOTE) in adults with obesity. The main questions it aims to answer are:
* Which of the three Internet-delivered weight loss programs results in the greatest weight loss?
* How do key weight-related behaviors (e.g., adherence, diet, physical activity) differ across the arms?
* What individual characteristics predict success in each arm?
* What are the underlying mechanisms of each approach?
* Are there any potential adverse outcomes associated with any of the conditions (e.g., depression, weight stigmatization, increased body image concerns).
Participants will:
* signed informed consent
* complete a baseline assessment
* be randomized to 12 months of either Standard iBWL, PREVENT or PROMOTE
* complete a training workshop to learn arm-specific cognitive strategies
* complete a 12-month Internet-delivered weight loss program, requiring self-monitoring of intake and exercise and viewing of 12 weekly lessons followed by 9 monthly lessons
* complete an assessment at 3 months (during treatment)
* complete a refresher workshop on arm-specific cognitive strategies at 3 months
* complete an assessment at 6 months (during treatment), 12 months (at the conclusion of treatment), and 18 months (6 months after treatment
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Participants will be between the ages of 18 and 70, have a BMI between 25 and 45 kg/m2, and have regular (i.e., weekly) access to the Internet, defined as owning a smart phone with Internet capabilities, and/or having a broadband or Wi-Fi connection at home or work.
Exclusion…
Inclusion Criteria:
* Participants will be between the ages of 18 and 70, have a BMI between 25 and 45 kg/m2, and have regular (i.e., weekly) access to the Internet, defined as owning a smart phone with Internet capabilities, and/or having a broadband or Wi-Fi connection at home or work.
Exclusion Criteria:
* Exclusionary criteria include: 1) current enrollment in a weight loss program, 2) currently taking weight loss medications, 3) history of bariatric surgery or planned bariatric surgery in the next 18 months, 4) individuals who are pregnant, nursing, or have plans to become pregnant within the next 18 months, 5) individuals planning to relocate outside the area in the next 18 months, 6) any medical condition for which weight loss would be contraindicated, 7) neurological or psychiatric conditions including but not limited to schizophrenia and bipolar disorder, 8) inability to attend assessments at the Weight Control and Diabetes Research Center in Providence, RI.
Individuals with mobility issues, dizziness, or history of heart disease, diabetes, or cancer will be required to provide physician consent prior to enrolling.
Contacts
No contact information available.
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