62 Recruiting Trials

Clinical Trials
for Obesity in Maryland

62 clinical trials for Obesity are currently recruiting participants at study sites in Maryland. Study-related care is provided at no cost.

62
Recruiting trials
56
Study sites
18
Cities
37
Industry-sponsored
4
Phase 2
27
Phase 3

Obesity clinical trials in Maryland: what to expect

Obesity trials are among the most actively recruiting studies in the United States right now. Most test medicines from the GLP-1 family (the class that includes semaglutide and tirzepatide) or newer compounds that work on the same appetite and blood-sugar pathways, often in people who also have high blood pressure, sleep apnea, knee osteoarthritis or prediabetes. A smaller number study structured diet and exercise programs, devices, or weight-loss surgery.

In Maryland, recruiting obesity studies are concentrated in Baltimore, Bethesda, Rockville and Columbia, with sites in 14 other cities. 37 of the 62 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who obesity trials usually look for

Nearly every study sets a body mass index (BMI) threshold, most often 30 or higher, or 27 or higher when you also have a weight-related condition. Many ask that your weight has been stable for the last three months and that you are not currently using a prescription weight-loss drug. Age limits of 18 to 75 are common. Pregnancy, a history of pancreatitis or certain thyroid cancers, and bariatric surgery within the last few years are the exclusions that come up most.

If you have type 2 diabetes, look for trials that name it: some obesity studies exclude diabetes, while others are designed specifically for people who have both.

What taking part involves

A screening visit with a physical exam, blood work and an ECG usually comes first. Drug trials then run for six months to two years, with study visits every few weeks at the start and every one to three months later on. Most GLP-1 studies use a once-weekly injection you give yourself at home; many are placebo-controlled, meaning some participants receive an inactive version for part or all of the study, and you are told that before you agree to join. Study medication, visits and tests are provided at no cost, and most trials pay a stipend for time and travel.

Questions worth asking the study team

Whether there is a placebo group and how long it lasts; whether you can continue the medicine after the study ends; how many visits are required and how far the site is from you; and what happens if you need to stop early. Sites answer these every day and a ten-minute phone screen is the normal next step.

Showing 20 of 62 recruiting Obesity trials in Maryland

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)
PHASE3 Birmingham, Alabama +4 sites NCT07654374
This trial is looking for adults with obesity or overweight who also have type 2 diabetes. Participants will take either the drug aleniglipron or a placebo for 76 weeks to assess its effects.
Recruiting
A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
PHASE3 Canoga Park, California +4 sites NCT07595549
This trial is looking for adults with overweight or obesity who may also have type 2 diabetes. Participants will get either a shot of the study medicine, berobenatide, or a placebo that doesn't contain any medicine. The study lasts for about 20 months and involves regular visits to check on health and weight.
Recruiting
Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS)
PHASE3 Tucson, Arizona +4 sites NCT07817875
This trial is looking for children aged 6 to less than 12 years who have obesity. Participants will try a new treatment along with healthy lifestyle changes for about two years.
Recruiting
A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)
PHASE3 Tucson, Arizona +4 sites NCT06672549
This trial is looking for teens aged 12 to under 18 who are struggling with obesity or being overweight. Participants must have tried losing weight before but were unsuccessful.
Recruiting
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)
PHASE3 Gilbert, Arizona +4 sites NCT07684144
This trial is looking for people with obesity and type 2 diabetes who have completed a previous study. Participants will take a medication to see how it works over a longer time period, while following specific rules during the trial.
Recruiting
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
PHASE3 Birmingham, Alabama +4 sites NCT07564414
This trial is looking for people with obesity, with or without type 2 diabetes, who want to lose weight. Participants will be assigned by chance to receive either CagriSema or semaglutide for about 83 weeks.
Recruiting
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
PHASE3 Tuscaloosa, Alabama +4 sites NCT07321886
This trial is looking for adults who are overweight or have obesity but do not have type 2 diabetes. Participants will take eloralintide for a main phase lasting about 75 weeks, with an option to continue for another 2 years if they have prediabetes.
Recruiting
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes
PHASE3 Birmingham, Alabama +4 sites NCT07743450
This trial is looking for adults with obesity or overweight who have type 2 diabetes. Participants will take a daily oral medication to see how well it works and how safe it is over time.
Recruiting
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities
PHASE3 Birmingham, Alabama +4 sites NCT07743463
This trial is looking for adults who are overweight or obese and have weight-related health problems. Participants will take a daily pill for the study to see how well it helps with weight management and its safety.
Recruiting
Efficacy and Safety of Ribupatide in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes
PHASE3 Anniston, Alabama +4 sites NCT07284875
This trial is looking for people who are overweight or living with obesity and have related health issues, but do not have diabetes. Participants will receive a weekly injection of ribupatide or a placebo to see how it affects their weight.
Recruiting
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
PHASE3 Alexander City, Alabama +4 sites NCT07567001
This trial is looking for individuals with heart failure who are also obese. Participants will receive either an injection of NNC0487-0111 or a placebo once a week to see how well it works and how safe it is.
Recruiting
Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)
PHASE3 Birmingham, Alabama +4 sites NCT07654361
This trial is looking for adults with obesity or overweight who have health problems related to their weight. Participants will take a daily medication called aleniglipron for at least 76 weeks while following a reduced-calorie diet and increasing physical activity.
Recruiting
A Research Study Investigating How a New Medicine NNC0113-5840 Works in People With Overweight or Obesity
PHASE1 Baltimore, Maryland +1 sites NCT07566390
This trial is looking for people who are overweight or have obesity to test a new medicine. Participants will either receive the new medicine NNC0113-5840 or a placebo that does not have any active ingredients.
Recruiting
Tailoring Mobile Health Technology to Reduce Obesity and Improve Cardiovascular Health in Resource-Limited Neighborhood Environments
NA Bethesda, Maryland NCT03288207
This trial is looking for African American women aged 21 to 75 who are overweight or obese and live in specific neighborhoods in Washington, DC, or nearby Maryland. Participants will use a smartphone app for coaching on increasing physical activity over a few months.
Recruiting
Mechanisms Underlying Individual Variations of Taste and Smell in Obesity
N/A Bethesda, Maryland NCT04714892
This trial is looking for adults aged 18-65, with and without obesity, to understand how taste and smell affect food choices. Participants will provide various samples and complete questionnaires about their eating habits and health.
Recruiting
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
PHASE3 Anniston, Alabama +4 sites NCT07351045
This trial is looking for adults who are overweight or have obesity without type 2 diabetes. Participants will take a study drug or a placebo to help with weight management and will need to self-administer the treatment.
Recruiting
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
PHASE3 Guntersville, Alabama +4 sites NCT07351058
This trial is looking for people with obesity or overweight and type 2 diabetes. Participants will use an injectable medication to help with weight management.
Recruiting
A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus
PHASE3 Escondido, California +4 sites NCT07776509
This trial is looking for adults with obesity or overweight who have related health problems. Participants will take a medication called AZD6234 and will be compared to others taking a placebo over 68 weeks.
Recruiting
A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight
PHASE3 Fairhope, Alabama +4 sites NCT07784270
This trial is looking for adults with type 2 diabetes and obesity or being overweight. Participants will take AZD6234 or a placebo for 68 weeks to see how it affects their body weight.
Recruiting
Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes
PHASE3 Cullman, Alabama +4 sites NCT07284901
This trial is looking for people with obesity or overweight who also have type 2 diabetes. Participants will receive a weekly injection of ribupatide to see how it affects their weight and blood sugar levels.
Recruiting

Where the Obesity studies are in Maryland

  • National Institutes of Health Clinical Center, Bethesda13 trials
  • Johns Hopkins University, Baltimore5 trials
  • Centennial Medical Group, Columbia4 trials
  • Ascension Saint Agnes Heart Care, Baltimore3 trials
  • PAREXEL Intl - EPCU-Baltimore, Baltimore3 trials
  • Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD, Baltimore2 trials

Counts are recruiting studies listing at least one site in Maryland, from ClinicalTrials.gov, refreshed every two days.

Obesity clinical trials in Maryland: common questions

How many Obesity clinical trials are recruiting in Maryland?
TrialFinder currently lists 62 recruiting Obesity clinical trials with study sites in Maryland. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Obesity clinical trials located in Maryland?
Study sites for the Obesity trials listed on this page include Baltimore, Bethesda. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Obesity clinical trial in Maryland?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Obesity trials in Maryland also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Obesity clinical trial in Maryland?
Each study sets its own criteria based on age, Obesity diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
Do I need a BMI over 30 to join an obesity clinical trial?
Most adult obesity trials require a BMI of 30 or higher, or 27 or higher if you also have a weight-related condition such as high blood pressure, prediabetes or sleep apnea. Each trial page lists its exact threshold.
Are obesity trial participants paid?
Study medication, visits and tests are provided free, and most obesity trials pay a stipend per visit for time and travel. The amount is set by each study and told to you before you enroll; it is never contingent on finishing the study.
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
All guides →

Check Your Eligibility

Create a free profile and our AI will match you to Obesity trials near you in Maryland.

Get Matched — Free
No insurance required

Obesity trials study GLP-1 receptor agonists, bariatric procedures, behavioural interventions, and combination weight-loss therapies in adults and adolescents.

All Obesity trials →