26 Recruiting Trials
Clinical Trials
for Kidney Disease in Maryland
26 clinical trials for Kidney Disease are currently recruiting participants at study sites in Maryland. Study-related care is provided at no cost.
26
Recruiting trials
32
Study sites
11
Cities
15
Industry-sponsored
7
Phase 2
7
Phase 3
Kidney Disease clinical trials in Maryland: what to expect
Kidney disease trials are mostly for chronic kidney disease that is slowly getting worse, including kidney disease caused by diabetes. They test medicines meant to slow the decline in kidney function and protect the heart, usually on top of the standard blood pressure and diabetes treatments. Specific kidney diseases such as IgA nephropathy, FSGS and polycystic kidney disease now have many trials of their own, and separate studies enroll people on dialysis or living with a transplant.
In Maryland, recruiting kidney disease studies are concentrated in Baltimore, Bethesda, Lutherville and Oxon Hill, with sites in 7 other cities. 15 of the 26 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.
Who kidney disease trials usually look for
Trials describe kidney disease by two numbers: the filtration rate (eGFR) from a blood test and the amount of protein in the urine. Most enroll an eGFR between about 20 and 75 and a urine protein level above a cut-off, both measured at screening. Nearly all ask that you have taken a stable dose of a blood-pressure medicine of the ACE inhibitor or ARB type for three months, and many allow or require an SGLT2 inhibitor. IgA nephropathy and FSGS trials need a past kidney biopsy. Common exclusions are a transplant, dialysis and uncontrolled blood pressure.
What taking part involves
Screening includes blood and urine tests, sometimes a 24-hour urine collection, and a review of your records. Trials then run one to three years with visits every four to twelve weeks for labs and blood pressure, taking a study pill or injection added to your usual medicines; placebo arms are common and an extension often follows. Your nephrologist keeps managing your care. Study medicine and tests are free and visits are usually paid.
Questions worth asking the study team
Which stage the trial enrolls and whether you fit it; whether any of your medicines change; how often labs are needed; the chance of placebo; and whether you will be told your own kidney results during the study.
Showing 20 of 26 recruiting Kidney Disease trials in Maryland
Immune System Related Kidney Disease
Recruiting
This trial is looking for adults and older children who have kidney diseases related to the immune system or conditions that could potentially lead to kidney disease. Participants will undergo health checks and tests to help researchers learn more about these conditions.
A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria
Recruiting
This trial is looking for children and young adults aged 1 to 18 who have chronic kidney disease and proteinuria. Participants will take a treatment called finerenone alongside their current heart medicine for about 18 months.
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)
Recruiting
This trial is looking for adults with chronic kidney disease who are at risk of it getting worse. Participants will take a study medicine called BI 690517 along with empagliflozin or just empagliflozin for the study duration.
A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)
Recruiting
This trial is looking for children aged 2 to 17 who have chronic kidney disease. Participants will take a daily tablet for 6 months followed by 1 year of another medication, with regular check-ups to monitor their health.
A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.
Recruiting
This trial is looking for adults with chronic kidney disease to see how well elecoglipron works compared to a placebo. Participants must be on certain medications for their condition before joining the study.
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
Recruiting
This trial is looking for adults with chronic kidney disease and high blood pressure. If you join, you will take medications to see how they affect your kidney health and heart-related risks.
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
Recruiting
This trial is looking for adults and children with a specific type of kidney disease caused by genetics. Participants will receive the drug VX-147 to assess its effectiveness and safety.
PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease
Recruiting
This trial is looking for adults and older teenagers with specific kidney diseases who have been stable on certain medications for at least a couple of months. They need to be in good enough health with manageable blood pressure. However, if you have had an organ transplant or recently used strong immunosuppressive treatments, you can't participate.
Bempedoic Acid Therapy for Polycystic Kidney Disease
Recruiting
This trial is looking for adults with autosomal dominant polycystic kidney disease (ADPKD) to test a new treatment. Participants will take bempedoic acid, which may help improve kidney function without the side effects of other treatments.
A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease
Recruiting
This trial is looking for adults with a specific genetic risk for kidney disease and ongoing protein in their urine. Participants will take the drug MZE829 to see how it affects their kidney condition.
Dose-Ranging Safety, Tolerability, and Efficacy Study of AZD2373 in Participants With APOL1-Mediated Kidney Disease
Recruiting
This trial is looking for adults of African descent with a specific type of kidney disease. Participants will take the drug AZD2373 and attend check-ups to see how well the treatment works and if it is safe.
Safety, Tolerability and Pharmacokinetics of AZD1613 in Adults With Autosomal Dominant Polycystic Kidney Disease
Recruiting
This trial is looking for adults with a specific type of kidney disease who can receive a new treatment called AZD1613. Participants will either receive the treatment through an injection under the skin or directly into the bloodstream and will be monitored for safety and how the body processes the drug.
PKD Clinical and Translational Core Study
Recruiting
This trial is looking for adults who have polycystic kidney disease (ADPKD) and are willing to contribute to research. Participants will help build a group of ADPKD patients and may provide samples for future studies.
A Multicenter, Prospective Blood Collection Study in a Kidney Transplant Population
Recruiting
This trial is looking for kidney transplant patients to provide blood samples and information. The goal is to help develop a test that checks how well the transplanted kidney is functioning.
Transforming Hemodialysis-Related Vascular Access Education
Recruiting
This trial is looking for adults with advanced chronic kidney disease. Participants will learn about hemodialysis access through different educational methods and share their experiences over about 12 months.
Incremental Hemodialysis: The TwoPlus Trial
Recruiting
This trial is looking for adults with kidney problems who need dialysis. Participants will either start a new type of dialysis called incremental hemodialysis or a traditional one. The trial will follow them for about two years to compare the outcomes.
Exercise and Monitoring With Post-Hospitalization Muscle Atrophy to Sustain Intrinsic Capacity and Strength
Recruiting
This trial is looking for older adults with chronic kidney disease who have been hospitalized. Participants will help improve recovery from muscle weakness after being in the hospital through exercise and monitoring.
An Observational Extension Study for Adult Patients Treated in Study R5459-RT-1944 Who Receive a Kidney Transplant
Recruiting
This trial is looking for adult patients who have received a kidney transplant and were treated with vonsetamig in a previous study. Participants will be monitored to see how their body responds after the transplant, but no study drug will be given during this trial.
A Study to See if Tolvaptan is Safe in Infants and Children Who at Enrollment Are 28 Days to Less Than 18 Years Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD)
Recruiting
This trial is looking for infants and children aged 28 days to under 18 years who have a diagnosis of Autosomal Recessive Polycystic Kidney Disease (ARPKD). Participants will take a medication called tolvaptan to evaluate its safety and how it works for their condition.
A Study to Assess the Effect of Surovatamig in Adult Participants With Antibody-mediated Kidney Disease
Recruiting
This trial is looking for adult participants with a specific kind of kidney disease called primary membranous nephropathy. Participants will receive a treatment called surovatamig through an injection to see how safe and effective it is.
Where the Kidney Disease studies are in Maryland
Research sites running the most studies
- Research Site, Bethesda3 trials
- Johns Hopkins Hospital, Baltimore2 trials
- Johns Hopkins University, Baltimore2 trials
- National Institutes of Health Clinical Center, Bethesda2 trials
- Research Site, Baltimore2 trials
- Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD, Baltimore1 trial
By city
Counts are recruiting studies listing at least one site in Maryland, from ClinicalTrials.gov, refreshed every two days.
Kidney Disease clinical trials in Maryland: common questions
How many Kidney Disease clinical trials are recruiting in Maryland?
TrialFinder currently lists 26 recruiting Kidney Disease clinical trials with study sites in Maryland. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Kidney Disease clinical trials located in Maryland?
Study sites for the Kidney Disease trials listed on this page include Bethesda, Baltimore. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Kidney Disease clinical trial in Maryland?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Kidney Disease trials in Maryland also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Kidney Disease clinical trial in Maryland?
Each study sets its own criteria based on age, Kidney Disease diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
What stage of kidney disease do trials look for?
Trials state an eGFR range and a urine protein threshold rather than a stage name; most cover stages 2 to 4. People on dialysis or with a transplant have separate trials written for them.
Do I need a kidney biopsy to join?
Trials for IgA nephropathy, FSGS and lupus nephritis require a past biopsy confirming the diagnosis. Trials for diabetic or general chronic kidney disease do not.
Will I keep my current kidney and blood pressure medicines?
Yes. Kidney trials add the study treatment to a stable regimen, usually including an ACE inhibitor or ARB, and your own nephrologist continues to manage them.
Kidney Disease Trials in Other States
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Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
All guides →
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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About Kidney Disease Trials
Kidney disease trials evaluate SGLT2 inhibitors, dialysis protocols, renal transplant regimens, and supportive-care strategies for chronic and acute kidney disease.
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