12 Recruiting Trials

Clinical Trials
for Kidney Disease in District of Columbia

12 clinical trials for Kidney Disease are currently recruiting participants at study sites in District of Columbia. Study-related care is provided at no cost.

12
Recruiting trials
10
Study sites
1
City
6
Industry-sponsored
2
Phase 2
5
Phase 3

Kidney Disease clinical trials in District of Columbia: what to expect

Kidney disease trials are mostly for chronic kidney disease that is slowly getting worse, including kidney disease caused by diabetes. They test medicines meant to slow the decline in kidney function and protect the heart, usually on top of the standard blood pressure and diabetes treatments. Specific kidney diseases such as IgA nephropathy, FSGS and polycystic kidney disease now have many trials of their own, and separate studies enroll people on dialysis or living with a transplant.

In District of Columbia, recruiting kidney disease studies are concentrated in Washington D.C.. 6 of the 12 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.

Who kidney disease trials usually look for

Trials describe kidney disease by two numbers: the filtration rate (eGFR) from a blood test and the amount of protein in the urine. Most enroll an eGFR between about 20 and 75 and a urine protein level above a cut-off, both measured at screening. Nearly all ask that you have taken a stable dose of a blood-pressure medicine of the ACE inhibitor or ARB type for three months, and many allow or require an SGLT2 inhibitor. IgA nephropathy and FSGS trials need a past kidney biopsy. Common exclusions are a transplant, dialysis and uncontrolled blood pressure.

What taking part involves

Screening includes blood and urine tests, sometimes a 24-hour urine collection, and a review of your records. Trials then run one to three years with visits every four to twelve weeks for labs and blood pressure, taking a study pill or injection added to your usual medicines; placebo arms are common and an extension often follows. Your nephrologist keeps managing your care. Study medicine and tests are free and visits are usually paid.

Questions worth asking the study team

Which stage the trial enrolls and whether you fit it; whether any of your medicines change; how often labs are needed; the chance of placebo; and whether you will be told your own kidney results during the study.

Showing 12 of 12 recruiting Kidney Disease trials in District of Columbia

A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria
PHASE3 Washington D.C., District of Columbia +4 sites NCT05457283
This trial is looking for children and young adults aged 1 to 18 who have chronic kidney disease and proteinuria. Participants will take a treatment called finerenone alongside their current heart medicine for about 18 months.
Recruiting
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
PHASE3 Fairhope, Alabama +4 sites NCT06742723
This trial is looking for adults with chronic kidney disease and high blood pressure. If you join, you will take medications to see how they affect your kidney health and heart-related risks.
Recruiting
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
PHASE2 Alabaster, Alabama +4 sites NCT05312879
This trial is looking for adults and children with a specific type of kidney disease caused by genetics. Participants will receive the drug VX-147 to assess its effectiveness and safety.
Recruiting
A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease
PHASE2 Decatur, Alabama +4 sites NCT06830629
This trial is looking for adults with a specific genetic risk for kidney disease and ongoing protein in their urine. Participants will take the drug MZE829 to see how it affects their kidney condition.
Recruiting
Effect of Empagliflozin on Podocyte Specific Proteins in African American Veterans With NDKD
PHASE4 Washington D.C., District of Columbia NCT06110130
This trial is looking for African American veterans with kidney disease who are interested in taking empagliflozin. Participants will provide urine samples to help researchers understand kidney health.
Recruiting
Effects of Combination Exercise on Fatigability in Veterans With Chronic Kidney Disease
NA Washington D.C., District of Columbia NCT04397159
This trial is looking for veterans aged 50 and older with chronic kidney disease who can walk with or without a walking aid. Participants will engage in a combination exercise program to help improve muscle function and reduce fatigue.
Recruiting
A Phase III Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With CKD Stage 3b and 4 (BalanceD-CKD)
PHASE3 Huntsville, Alabama +4 sites NCT07624305
This trial is looking for adults with chronic kidney disease stages 3b and 4. Participants will take a daily combination of two medications to see how well they work together compared to taking just one of them.
Recruiting
A Study to See if Tolvaptan is Safe in Infants and Children Who at Enrollment Are 28 Days to Less Than 18 Years Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD)
PHASE3 Washington D.C., District of Columbia +4 sites NCT04782258
This trial is looking for infants and children aged 28 days to under 18 years who have a diagnosis of Autosomal Recessive Polycystic Kidney Disease (ARPKD). Participants will take a medication called tolvaptan to evaluate its safety and how it works for their condition.
Recruiting
Autosomal Dominant Polycystic Kidney Disease (ADPKD) Study
N/A Washington D.C., District of Columbia +3 sites NCT04338048
This trial is looking for people diagnosed with Autosomal Dominant Polycystic Kidney Disease (ADPKD) to learn more about the condition and improve resources for others. Participants may share their clinical information and may take part in related research.
Recruiting
Accelerated Age-related Cognitive Decline: Impact of Exercise on Executive Function and Neuroplasticity
NA Washington D.C., District of Columbia +1 sites NCT05655325
This trial is looking for older adults with chronic kidney disease and mild cognitive impairment. Participants will take part in a 6-month walking program at home to see if it helps improve memory and brain function.
Recruiting
A Cardiometabolic Health Program Linked With Clinical-Community Support and Mobile Health Telemonitoring to Reduce Health Disparities
NA Washington D.C., District of Columbia +2 sites NCT05321368
This trial is looking for adults with high blood pressure and either diabetes or chronic kidney disease. Participants will use a home blood pressure monitor and get support from healthcare providers to manage their conditions better.
Recruiting
ARPKD Database Study
N/A Washington D.C., District of Columbia +4 sites NCT01401998
This trial is looking for people with certain rare liver and kidney diseases. Participants will provide clinical information and may also share DNA or tissue samples to help improve understanding and treatment of these conditions.
Recruiting

Where the Kidney Disease studies are in District of Columbia

  • Research Site, Washington D.C.3 trials
  • Children's National Hospital, Washington D.C.2 trials
  • Children's National Hospital - Nephrology, Washington D.C.2 trials
  • Children's National Medical Center, Washington D.C.1 trial
  • Georgetown University, Washington D.C.1 trial
  • The George Washington University - GW Medical Faculty Associates, Washington D.C.1 trial

Counts are recruiting studies listing at least one site in District of Columbia, from ClinicalTrials.gov, refreshed every two days.

Kidney Disease clinical trials in District of Columbia: common questions

How many Kidney Disease clinical trials are recruiting in District of Columbia?
TrialFinder currently lists 12 recruiting Kidney Disease clinical trials with study sites in District of Columbia. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Kidney Disease clinical trials located in District of Columbia?
Study sites for the Kidney Disease trials listed on this page include Washington D.C.. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Kidney Disease clinical trial in District of Columbia?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Kidney Disease trials in District of Columbia also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Kidney Disease clinical trial in District of Columbia?
Each study sets its own criteria based on age, Kidney Disease diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
What stage of kidney disease do trials look for?
Trials state an eGFR range and a urine protein threshold rather than a stage name; most cover stages 2 to 4. People on dialysis or with a transplant have separate trials written for them.
Do I need a kidney biopsy to join?
Trials for IgA nephropathy, FSGS and lupus nephritis require a past biopsy confirming the diagnosis. Trials for diabetic or general chronic kidney disease do not.
Will I keep my current kidney and blood pressure medicines?
Yes. Kidney trials add the study treatment to a stable regimen, usually including an ACE inhibitor or ARB, and your own nephrologist continues to manage them.
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Kidney disease trials evaluate SGLT2 inhibitors, dialysis protocols, renal transplant regimens, and supportive-care strategies for chronic and acute kidney disease.

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