22 Recruiting Trials
Clinical Trials
for Kidney Disease in Alabama
22 clinical trials for Kidney Disease are currently recruiting participants at study sites in Alabama. Study-related care is provided at no cost.
22
Recruiting trials
26
Study sites
8
Cities
15
Industry-sponsored
8
Phase 2
7
Phase 3
Kidney Disease clinical trials in Alabama: what to expect
Kidney disease trials are mostly for chronic kidney disease that is slowly getting worse, including kidney disease caused by diabetes. They test medicines meant to slow the decline in kidney function and protect the heart, usually on top of the standard blood pressure and diabetes treatments. Specific kidney diseases such as IgA nephropathy, FSGS and polycystic kidney disease now have many trials of their own, and separate studies enroll people on dialysis or living with a transplant.
In Alabama, recruiting kidney disease studies are concentrated in Birmingham, Huntsville, Montgomery and Decatur, with sites in 4 other cities. 15 of the 22 are run by a drug or device company, which usually means a larger study with travel reimbursement; the rest are academic or hospital-led.
Who kidney disease trials usually look for
Trials describe kidney disease by two numbers: the filtration rate (eGFR) from a blood test and the amount of protein in the urine. Most enroll an eGFR between about 20 and 75 and a urine protein level above a cut-off, both measured at screening. Nearly all ask that you have taken a stable dose of a blood-pressure medicine of the ACE inhibitor or ARB type for three months, and many allow or require an SGLT2 inhibitor. IgA nephropathy and FSGS trials need a past kidney biopsy. Common exclusions are a transplant, dialysis and uncontrolled blood pressure.
What taking part involves
Screening includes blood and urine tests, sometimes a 24-hour urine collection, and a review of your records. Trials then run one to three years with visits every four to twelve weeks for labs and blood pressure, taking a study pill or injection added to your usual medicines; placebo arms are common and an extension often follows. Your nephrologist keeps managing your care. Study medicine and tests are free and visits are usually paid.
Questions worth asking the study team
Which stage the trial enrolls and whether you fit it; whether any of your medicines change; how often labs are needed; the chance of placebo; and whether you will be told your own kidney results during the study.
Showing 20 of 22 recruiting Kidney Disease trials in Alabama
A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)
Recruiting
This trial is looking for children aged 2 to 17 who have chronic kidney disease. Participants will take a daily tablet for 6 months followed by 1 year of another medication, with regular check-ups to monitor their health.
A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.
Recruiting
This trial is looking for adults with chronic kidney disease to see how well elecoglipron works compared to a placebo. Participants must be on certain medications for their condition before joining the study.
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
Recruiting
This trial is looking for adults with end stage kidney disease who are undergoing dialysis and have systemic inflammation. Participants will receive a study medication or a placebo to see how it affects heart health.
Study to Assess the Effects of ALN-ANG3 in Adult Participants With Diabetic Kidney Disease
Recruiting
This trial is looking for adults with diabetic kidney disease to test some new medications. Participants will help researchers understand how safe and effective these medications are.
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
Recruiting
This trial is looking for adults with chronic kidney disease and high blood pressure. If you join, you will take medications to see how they affect your kidney health and heart-related risks.
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
Recruiting
This trial is looking for adults and children with a specific type of kidney disease caused by genetics. Participants will receive the drug VX-147 to assess its effectiveness and safety.
PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease
Recruiting
This trial is looking for adults and older teenagers with specific kidney diseases who have been stable on certain medications for at least a couple of months. They need to be in good enough health with manageable blood pressure. However, if you have had an organ transplant or recently used strong immunosuppressive treatments, you can't participate.
ANCHOR Study: A Study to Assess the Safety and Efficacy of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Recruiting
This trial is looking for adults with a specific type of kidney disease. Participants will receive either the study drug or a placebo every 4 weeks for 92 weeks and will attend regular check-ups.
A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease
Recruiting
This trial is looking for adults with a specific genetic risk for kidney disease and ongoing protein in their urine. Participants will take the drug MZE829 to see how it affects their kidney condition.
Safety, Tolerability and Pharmacokinetics of AZD1613 in Adults With Autosomal Dominant Polycystic Kidney Disease
Recruiting
This trial is looking for adults with a specific type of kidney disease who can receive a new treatment called AZD1613. Participants will either receive the treatment through an injection under the skin or directly into the bloodstream and will be monitored for safety and how the body processes the drug.
A Study of Mezagitamab in Adults With Kidney Condition Called IgA Nephropathy
Recruiting
This trial is looking for adults with a kidney condition called IgA nephropathy. Participants will receive either mezagitamab or a placebo for 22 weeks and then be monitored for about 1.5 years.
Pivotal Study of the Velocity™ pAVF System
Recruiting
This trial is looking for adults with kidney failure who need a way to access dialysis. Participants will receive a new procedure to create a dialysis access point with a small puncture instead of open surgery, followed by regular check-ups for up to five years.
Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 1) (IRIS-CKD)
Recruiting
This trial is looking for adults with type 2 diabetes to improve kidney screening. Participants will need to have had a visit with their primary doctor in the last two years and haven't had certain kidney tests in the past 15 months.
Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2)
Recruiting
This trial is looking for adults with type 2 diabetes who have been diagnosed with chronic kidney disease. Participants will receive improved care and management for their kidney health through this program.
A Stakeholder-enhanced Intervention to Improve the Decisional Partnership of Chronic Kidney Disease Dyads (IMPART)
Recruiting
This trial is looking for patients with stage 4 chronic kidney disease and their caregivers. Participants will receive training to help improve decision-making and support for managing the patient's condition.
A Phase III Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With CKD Stage 3b and 4 (BalanceD-CKD)
Recruiting
This trial is looking for adults with chronic kidney disease stages 3b and 4. Participants will take a daily combination of two medications to see how well they work together compared to taking just one of them.
A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)
Recruiting
This trial is looking for healthy adults or adults with end-stage kidney disease on hemodialysis. Participants will receive a medication called AZD7760 through an intravenous infusion to study its safety and how it moves through the body.
PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes
Recruiting
This trial is looking for people with type 2 diabetes and heart disease or at high risk for heart disease. Participants will take one of two medications and will be monitored for heart, kidney, and death-related events over time.
Inspire HER: Inspiring the Heart and Emotions for Radical Health
Recruiting
This trial is looking for Black women aged 30 to 79 who want to improve their heart health. Participants will take part in a program that offers health education, physical activity, and support resources.
A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia
Recruiting
This trial is looking for adults with high phosphate levels who are on dialysis. Participants will take a medication called AP306 while continuing their regular dialysis treatments.
Where the Kidney Disease studies are in Alabama
Research sites running the most studies
- Research Site, Huntsville4 trials
- University of Alabama at Birmingham, Birmingham4 trials
- Nephrology Consultants, LLC, Huntsville3 trials
- Apogee Clinical Research, LLC, Huntsville2 trials
- Research Site, Montgomery2 trials
- University of Alabama, Birmingham2 trials
By city
Counts are recruiting studies listing at least one site in Alabama, from ClinicalTrials.gov, refreshed every two days.
Kidney Disease clinical trials in Alabama: common questions
How many Kidney Disease clinical trials are recruiting in Alabama?
TrialFinder currently lists 22 recruiting Kidney Disease clinical trials with study sites in Alabama. Results are updated regularly from ClinicalTrials.gov, the official U.S. registry of clinical studies.
Where are Kidney Disease clinical trials located in Alabama?
Study sites for the Kidney Disease trials listed on this page include Birmingham, Huntsville, Decatur, Fairhope, Alabaster, Dothan. Each trial page lists every participating site with contact details, so you can find the location closest to you.
Do I need insurance to join a Kidney Disease clinical trial in Alabama?
No. Study-related care is covered by the trial sponsor at no cost to participants, including the study treatment, required lab tests and study visits. Many Kidney Disease trials in Alabama also compensate participants for time and travel. Health insurance is not required to search or enroll.
How do I qualify for a Kidney Disease clinical trial in Alabama?
Each study sets its own criteria based on age, Kidney Disease diagnosis details, prior treatments, current medications and general health. The fastest way to find out is to contact a research site directly — most will pre-screen you by phone in 10 to 15 minutes at no charge. You can also create a free TrialFinder profile to be matched automatically.
What stage of kidney disease do trials look for?
Trials state an eGFR range and a urine protein threshold rather than a stage name; most cover stages 2 to 4. People on dialysis or with a transplant have separate trials written for them.
Do I need a kidney biopsy to join?
Trials for IgA nephropathy, FSGS and lupus nephritis require a past biopsy confirming the diagnosis. Trials for diabetic or general chronic kidney disease do not.
Will I keep my current kidney and blood pressure medicines?
Yes. Kidney trials add the study treatment to a stable regimen, usually including an ACE inhibitor or ARB, and your own nephrologist continues to manage them.
Kidney Disease Trials in Other States
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Helpful Reading
Are Clinical Trials Safe? What Patients Should Know
How clinical trial safety works — phases, IRB oversight, informed consent, and your right to withdraw — plus the real risks and questions to ask.
How to Know If You Qualify for a Clinical Trial
Every trial has eligibility criteria based on diagnosis, age, and medical history. Here's how to tell if you qualify — and what to do if you're not sure.
Clinical Trials Without Insurance: What You Need to Know
All guides →
Clinical trials cover the cost of study-related care, making them one of the few ways to access treatment without health insurance. Here's what's covered.
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About Kidney Disease Trials
Kidney disease trials evaluate SGLT2 inhibitors, dialysis protocols, renal transplant regimens, and supportive-care strategies for chronic and acute kidney disease.
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